01-02-2012 13:37 Meet founders of Cord Blood Registry, Tom and Wendy. Hear why they started CBR -- a family business dedicated to helping people live healthier lives through cord blood stem cell medicine. Today, CBR has grown, but the attention to healthy families is the same. For more than 15 years, Cord Blood Registry has led the umbilical cord banking industry in technical innovations and provided families with peace of mind and hope. CBR's experience and dedication to quality has enabled CBR to help more clients use their cord blood stem cells in treatments than any other family bank. Our research and development efforts are focused on helping leading clinical researchers advance stem cell regenerative medicine that may help families in the future. Ultimate use of cord blood stem cells will be determined by the treating physician who will consider if they are applicable for the condition and should come from the patient or a suitable donor (like an HLA matched sibling). There is no guarantee that treatments being studied in the laboratory or in clinical trials will be available in the future. CBR is the preferred choice of OB/Gyns. © 2011 Cord Blood Registry. All rights reserved. Privacy Policy.

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Meet the Founders of Cord Blood Registry - Video

16-01-2012 16:52 On October 1st, 2009 I was diagnosed with Leukemia. After 9 months of intense chemotherapy treatments, the decision was made that I would need a bone marrow transplant. A suitable donor was not found within my family so I would have to rely on the national Be The Match® marrow registry to locate one for me. A match was found and on August 18th, 2010 I underwent a stem-cell transplant using an unrelated donors stem-cells. Today, I'm cancer free! Her generosity and selflessness has allowed me to call myself a 'survivor'. This video was captured of my donor and I meeting face-to-face for the first time. It was truly an amazing experience! I have made it my life's mission to 'Pay it Forward'. After transplant, I started working for The Leukemia and Lymphoma Society where I am able to use my wounds for good on a daily basis. My diagnoses was not in vain! To learn how you can help create a world without cancer, visit http://www.LLS.org and to join the Be The Match® registry, visit join.marrow.org

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Leukemia Survivor Meets His Bone Marrow Donor - Video

The work has implications in two areas. In cancer treatment, it is desirable to inhibit cell proliferation. But to grow adult stem cells for transplantation to victims of injury or disease, it would be desirable to sustain proliferation until a sufficient number of cells have been produced to make a usable organ or tissue.

The study gives researchers a handle on how those two competing processes might be controlled. It was performed at the university's Hormel Institute in Austin, Minn., using mouse stem cells. The researchers, led by Hormel Institute Executive Director Zigang Dong and Associate Director Ann M. Bode, have published a report in the journal Nature Structure and Molecular Biology.

"This is breakthrough research and provides the molecular basis for development of regenerative medicine," said Dong. "This research will aid in the development of the next generation of drugs that make repairs and regeneration within the body possible following damage by such factors as cancer, aging, heart disease, diabetes, or paralysis caused by traumatic injury."

The mechanism centers on a protein called Klf4, which is found in embryonic stem cells and whose activities include keeping those cells dividing and proliferating rather than differentiating. That is, Klf4 maintains the character of the stem cells; this process is called self-renewal. The researchers discovered that two enzymes, called ERK1 and ERK2, inactivate Klf; this allows the cells to begin differentiating into adult cells.

The two enzymes are part of a "bucket brigade" of signals that starts when a chemical messenger arrives from outside the embryonic stem cells. Chemical messages are passed to inside the cells, resulting in, among other things, the two enzymes swinging into action.

The researchers also discovered how the enzymes control Klf4. They attach a small molecule--phosphate, consisting of phosphorus and oxygen--to Klf4. This "tag" marks it for destruction by the cellular machinery that recycles proteins.

Further, they found that suppressing the activity of the two enzymes allows the stem cells to maintain their self-renewal and resist differentiation. Taken together, their findings paint a picture of the ERK1 and ERK2 enzymes as major players in deciding the future of embryonic stem cells--and potentially cancer cells, whose rapid growth mirrors the behavior of the stem cells.

Klf4 is one of several factors used to reprogram certain adult skin cells to become a form of stem cells called iPS (induced pluripotent stem) cells, which behave similarly to embryonic stem cells. Also, many studies have shown that Klf4 can either activate or repress the functioning of genes and, in certain contexts, act as either an oncogene (that promotes cancer) or a tumor suppressor. Given these and their own findings reported here, the Hormel Institute researchers suggest that the self-renewal program of cancer cells might resemble that of embryonic stem cells.

"Although the functions of Klf4 in cancer are controversial, several reports suggest Klf4 is involved in human cancer development," Bode said.

Provided by University of Minnesota (news : web)

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New study makes key finding in stem cell self-renewal

NEW YORK--(BUSINESS WIRE)--

IntelliCell BioSciences, Inc. (OTCQB: SVFC.PK) (PINKSHEETS: SVFC.PK); (“IntelliCell”) or the (“Company”), was invited to demonstrate its stromal vascular fraction technology at the recent Baseball Injuries Symposium at the Andrews Sports Medicine Institute in Alabama held and sponsored by USA Baseball. The course Chairman is Dr. James Andrews, and moderated by PT Kevin Wilk, and Dr. Jeff Dugas. One of the courses presented during the three day event was on stem cell technology presented by Dr. Joshua Hackel. Dr. Hackel presented the state of regenerative medicine technology in the role of treating sports injuries. The link is http://www.mediafire.com/?u7bfa662e3r1sdp.

Dr. Hackel compared the IntelliCell SVF technology to several other methods of regenerative medicine being considered to be used by the leading orthopedic sports medicine doctors. Dr. Steven Victor, CEO of IntelliCell stated, "We are extremely excited that IntelliCell’s technology compares very favorably to all the other technologies, for procedures common to all major sports industries. We are extremely grateful to have the opportunity to present to over 200 leading doctors and trainers looking to treat major league, collegiate and amateur baseball players with regenerative medicine. IntelliCell Biosciences believes that its technology will be utilized by such experts this year."

About IntelliCell BioSciences, Inc.

IntelliCell is a pioneering regenerative medicine company focused on the expanding regenerative medical markets using stromal vascular fraction derived from adult adipose tissue. IntelliCell intends to initially focus on selling laboratory suites and licensing its technology to doctors for use in their offices for their patients. The company is also setting up Centers of Excellence where doctors can treat their patients. In addition, IntelliCell BioSciences is exploring storing the stromal vascular fraction in cryo-storage for future uses. The company is also starting FDA IND clinical trials at major medical centers for clinical indication approval. IntelliCell intends to pursue expansion to secondary markets and beyond the U.S. through a combination of company-owned and licensed clinical facilities.

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IntelliCell Demonstrates at the American Sports Medicine Institute Held in Conjunction with and at the Andrews Sports ...

02-09-2011 03:47 metromd.net Stem Cells to Treat Acne Scarring | An overview by Alex Martin, MD of how he combines stem cell therapy and the CO2 fractional laser to effectively treat facial scars caused by acne. Offices near Hollywood, Beverly Hills, Los Angeles and Orange County. Questions? Please call the MetroMD Institute of Regenerative Medicine at (323) 285-5300 or email us at info@MetroMD.net.

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Stem Cells to Treat Acne Scarring | Los Angeles | Hollywood | Beverly Hills - Video

01-02-2012 21:36 Notes from the interview: Nicholas Anderson - Author, NOC: British Secret Operations Big Pharma... must be careful in discussing reason for writing books is in part because of something along these lines medical doctor helped to exfiltrate from soviet union end of 1991 doctor wanted to meet... nicholas anderson flew to meet in moscow... bottom line: he claimed to have number of effective treatments and cures... MIND YOU... he's not trying to get your hopes up, but you should look into alternate treatments natural remedies. stem cell, energetic medicine is more detail in the book? when the book was written, it was non-fiction. but it didn't last to be a non-fiction novel. former secret operations must be cleared. large majority that was redacted or cleared from the fiction novel was about big pharma. certain things -are- in the book. also know that nicholas anderson was skeptical about these items first. even so, he wondered why aren't these alternative cures more widely known? the doctor appeared on a primetime show and the media prevented him from saying what he wanted to say... in a couple examples, they removed things he had said. they said the -opposite- of what he actually said. it was then that he realized he was on to something and he saw that happening. did this doctor have access to this medicine in the soviet union or was it secretive? in the beginning of communism, they did come up with things in medicine that the west never did come up with. this doctor had ...

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NOC Interview 2: Big Pharma - Video

STAMFORD -- Justin Wexler, 12, a seventh-grader at Scofield Magnet Middle School, is asking Stamford residents to "be a super hero on Super Bowl Sunday" by registering to be a bone marrow donor.

Justin is hosting a donor drive at the Jewish Community Center, at 1035 Newfield Ave., from 10 a.m. to 2 p.m. on Sunday for his mitzvah project, a contribution to the community before his bar mitzvah.

"Don't worry, there's plenty of time to do this early in the day and get back home in time to watch the game," said Justin, who will be rooting for the Giants on Sunday.

The donor drive will take about 6 minutes for each participant from start to finish, he explained, calmly spelling out the detailed process step-by-step as he sat at the head of his family's dining room table Tuesday afternoon, his bright blue eyes shining.

"You walk into the JCC, and first you'll come to a station and they'll tell you the eligibility requirements ¦ then you fill out a basic registration form and go off to the swabbing station," he said. Each donor will then take a swab from the inside of their left and right cheek and wrap their samples up with their information.

"That's it. It doesn't take long," he said. "But think about what could come from it."

Justin came up with the idea for a bone marrow drive around Thanksgiving, as he and his mother reflected on his father's experiences as a bone marrow donor for a woman in Long Island about two years ago. Justin's grandfather also donated bone marrow before Justin was born. The idea that his family members were able to save others' lives so easily stuck with him.

There are nearly 3 million potential donors registered with DKMS, the bone marrow donor center through which Justin will run his drive. But with a new diagnosis every four minutes, the donor reserves still aren't enough; 60 percent of bone cancer patients never receive the transplants they need.

"It's like finding a needle in a haystack," Justin said. His hope is that his drive will add 180 new names to that registry, and that someone will someday be a match for someone else in need. He chose the number 180 because it is a multiple of 18, a spiritual number in the Jewish faith that has strong ties to "life."

"It's mitzvah, and trying to give someone else a life, so we thought 180 would be a good goal," he said.

While Justin said he is hoping to sign up scores of potential donors, he stressed that people should not register if they're not absolutely certain they will be willing to go through with the transplant. He mentioned a boy around his age in Texas that he met around the holidays, who recently found a non-related donor for his second transplant after a transplant from his brother did not work as well as he and his doctors had anticipated.

"Imagine if they found him a match and then they said no," Justin said.

There are two ways to donate if a match is found. About 80 percent of the time, a donor's blood is removed from one arm with a needle, blood stem cells are filtered out and the remaining blood is pumped back into the other arm. In the other method, marrow cells are collected from a donor using a special syringe.

The first option can often take two days, while the second takes about one or two hours in outpatient surgery. While flu-like side effects can occur for about 48 hours after the first option, donors usually experience some pain, bruising and stiffness for up to two weeks after the second option, according to DKMS.

"I think most people when they find out someone has cancer, they feel helpless, but this could be an opportunity to save someone's life," said Justin's mother, Robin Wexler.

Justin's not old enough to swab his own cheeks for the cause -- donors have to be between the ages of 18 and 55 -- but he said he is glad to be helping by spreading the word.

"Maybe someone will show up on Sunday, someone who's never even thought about doing this before, and maybe that person will be a match; maybe they'll save a life," he said. "Imagine that."

Staff writer Maggie Gordon can be reached at maggie.gordon@scni.com or 203-964-2229.

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Stamford boy hosting bone marrow donor drive Sunday

31-01-2012 20:35 http://www.singularityweblog.com This morning I interviewed Daniel Kraft for Singularity 1 on 1. I met Dr. Kraft at Singularity University where he is the Medicine and Neuroscience Chair and executive director of the FutureMed Program. Daniel is one of those people with an incredibly diverse spectrum of talents and interests for he is not only a medical doctor and oncologist but also an inventor, a technology and space enthusiast, an entrepreneur and an F-16 flight surgeon. During our conversation we discuss a variety of topics such as: Daniel's early interest and talent in technology and science; his original fascination with the Apollo Space program and eventual participation in International Space University; his passion for flying and being a pilot; his medical education and personal journey to becoming a faculty member at Singularity University; his desire to be an instigator, connector and motivator of innovation; the story behind as well as the purpose and structure of the FutureMed program; bone marrow harvesting, regenerative medicine and stem cell research; longevity and the future of medicine and health care; his greatest inspiration and concerns about the field of medicine and his belief that one doesn't have to be a doctor to improve health care.

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Daniel Kraft on Singularity 1 on 1 (part 3) - Video

24-01-2012 18:39 Four minute excerpt from the Spotlight on Genomics seminar presentation during the January 17th 2012 California Institute for Regnerative Medicine governing board meeting. The video features a conversation between Catriona Jamieson, director for stem cell research at UCSD Moores Cancer Center, and one of her patients who is participating in a clinical trial for the treatment of myelofibrosis, a life-threatening blood disorder.

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Clinical Trial for Myelofibrosis that Targets Cancer Stem Cells | CIRM Spotlight on Genomics - Video

31-01-2012 19:41 http://www.singularityweblog.com This morning I interviewed Daniel Kraft for Singularity 1 on 1. I met Dr. Kraft at Singularity University where he is the Medicine and Neuroscience Chair and executive director of the FutureMed Program. Daniel is one of those people with an incredibly diverse spectrum of talents and interests for he is not only a medical doctor and oncologist but also an inventor, a technology and space enthusiast, an entrepreneur and an F-16 flight surgeon. During our conversation we discuss a variety of topics such as: Daniel's early interest and talent in technology and science; his original fascination with the Apollo Space program and eventual participation in International Space University; his passion for flying and being a pilot; his medical education and personal journey to becoming a faculty member at Singularity University; his desire to be an instigator, connector and motivator of innovation; the story behind as well as the purpose and structure of the FutureMed program; bone marrow harvesting, regenerative medicine and stem cell research; longevity and the future of medicine and health care; his greatest inspiration and concerns about the field of medicine and his belief that one doesn't have to be a doctor to improve health care.

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Daniel Kraft on Singularity 1 on 1 (part 2) - Video

Sangeeta Bhatia, MIT professor of health sciences and technology and electrical engineering and computer science

Researchers at MIT and their colleagues said they have devised a way to produce liver-like cells from stem cells, a key step in studying why people respond differently to Hepatitis C.andnbsp;andnbsp;andnbsp;andnbsp;andnbsp;andnbsp;andnbsp;andnbsp;
andnbsp;andnbsp;andnbsp;andnbsp;andnbsp;
An infectious disease that can cause inflammation and organ failure, Hepatitis C has different effects on different people, but no one is sure why, the researchers said in a press release from MIT. Some people are very susceptible to the infection, while others are resistant.

The researchers said that by studying liver cells from different people in the lab, they may determine how genetic differences produce these varying responses. However, liver cells are hard to get and very difficult to grow in a lab dish because they tend to lose their normal structure and function when removed from the body.

The researchers, from MIT, Rockefeller University and the Medical College of Wisconsin, have come up with a way to produce liver-like cells from induced pluripotent stem cells (iPSCs), which are made from body tissues rather than embryos. Those liver-like cells can then be infected with Hepatitis C and help scientists study the varying responses to the infection.

The scientists claim this is the first time an infection has been made in cells derived from iPSCs. Their new technique is described in the Jan. 30 issue of the Proceedings of the National Academy of Sciences. The development, they said, may also eventually enable personalized medicine, in which doctors could test the effect of different drugs on tissues derived from the patient being treated and then customize therapy for that patient.

The new study is a collaboration between Sangeeta Bhatia, professor of health sciences and technology and electrical engineering and computer science at MIT; Charles Rice, professor of virology at Rockefeller; and Stephen Duncan, professor of human and molecular genetics at the Medical College of Wisconsin.

The iPSCs are derived from normal body cells, often skin cells. By turning on certain genes in those cells, the scientists can revert them to an immature state that is identical to embryonic stem cells, which can turn into any cell type. Once the cells become pluripotent, they can be directed to become liver-like cells by turning on genes that control liver development.

The researchers’ goal is to take cells from patients who have unusual reactions to hepatitis C infection, transform them into liver cells and study their genetics to see why people respond as they do. “Hepatitis C virus causes an unusually robust infection in some people, while others are very good at clearing it. It’s not yet known why those differences exist,” Bhatia said in a statement.

Bhatia is a 2009 Mass High Tech Women to Watch honoree.
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Stem cells may shed light on hepatitis, MIT researchers find

03-01-2012 20:39 perfectmyskin.com - We often hear this "Build your own dreams before someone else HIRES you to build their dreams!". "Jeunesse", is once again in the forefront of this exploration for youth-enhancing solutions.

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Luminesce Stem Cell Skin Care - Rediscover Your Skin | Rediscover Yourself! - Video

19-12-2011 14:50 Katie Sharify, 23, of Pleasanton, receives stem cells for a spinal cord injury.

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Stem cell therapy at VMC - Video

26-10-2011 11:37 Apple Stem Cell break through technology that offers hopes for damaged skin.

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Apple Stem Cell - Video

09-11-2011 14:00 Olga Momcilovic speaks at the 2011 CIRM Grantee Meeting about the use of induced pluripotent stem (iPS) cells to better understand the causes of Parkinson's and to develop therapies. Momcilovic is a CIRM Scholar and postdoctoral research fellow at the Buck Institute located in Novato, California.

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Parkinson's Disease: Advancing Stem Cell Therapies - 2011 CIRM Grantee Meeting - Video

31-03-2011 09:39

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Bone marrow / Stem cell transplant - in isolation baby Yasmina tells a story. - Video

17-10-2011 14:27 This video, is a testimonial of a patient California that went to Progencell, for a Stem cell treatment for his ALS.

Link:
ALS - Stem Cell therapy (English) - Video

26-09-2011 18:57 Lean back and learn in just 3 minutes all benefits of our unique biological health care measure. (We) Back-up Your Life! TICEBA is the first private tissue bank worldwide to obtain stem cells from the skin, assess their quality and preserve them.

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TICEBA presents - Back-up Your Life! - Video

18-11-2011 14:29 Dr Tony Talebi discusses stem cell transplantation in Myeloma with Dr Ratzan. For further discussion visit http://www.HemOnc101.com.

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Dr Tony Talebi discusses stem cell transplantation in Myeloma with Dr Ratzan - Video

Our family's trip to Costa Rica (Feb 2009) for stem cell therapy for our autistic son. Includes Phoenix airport, Houston airport and hotel, San Jose airport and hotel (The Apartotel Cristina), The Institute for Cellular Medicine (Drs

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Autism Stem Cell Trip - Video