Gold River, CA (PRWEB) April 27, 2014

SkinStore.com, the nations leading e-commerce specialty retailer with over 9000 products for healing and maintaining healthy skin, has added Peter Thomas Roth Rose Stem Cell Bio Repair to its assortment of premium products.

Using state-of-the-art breakthrough stem cell technology, Peter Thomas Roth blended five rose stem cells with four rose extracts to create luxurious, effective anti-aging products. The Peter Thomas Roth Rose Stem Cell Bio-Repair Gel Mask is a cooling, revitalizing gel designed to promote cell turnover. Strengthening and rejuvenating the skin, the soothing mask improves the appearance of fine lines and wrinkles as well as dullness and dehydration, leaving skin radiant. Cleansing is a vital part of any skin care regimen, but a cleanser can do more than just remove makeup and environmental impurities. Glycolic acid combined with rose water, rose hip seed and other extracts plus rose stem cells make Peter Thomas Roth Rose Stem Cell Bio-Repair Cleansing Gel highly effective at sweeping away dead skin surface cells to reveal fresh, young-looking skin.

Christina Bertolino, Senior Buying Manager at SkinStore.com, said, Peter Thomas Roth is known industry-wide for effective products that produce clinically-proven results. With their cutting-edge plant stem cell technology theyve created a breakthrough in anti-aging.

About SkinStore.com. Physician-founded in 1997, SkinStore carries over 300 premium brands of skin care, cosmetics, hair care, beauty tools and fragrances from around the world. With over 9,000 products to choose from, SkinStore is a leading online resource for clinical and dermatologist-recommended skin care products. Customers receive free shipping on all U.S. orders over $49, and an esthetician-staffed call center is available Monday through Friday to answer questions and offer product recommendations. The company is headquartered in Gold River (Sacramento), California with operations in Sydney, Australia and an affiliate in Hangzhou, China. For more information visit SkinStore.com, SkincareStore.com.au, or SkinStorechina.com

Contact Information Denise McDonald, Content & Production Manager SkinStore http://www.skinstore.com 916-475-1427

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SkinStore.com Announces the Addition of Peter Thomas Roth Rose Stem Cell Bio-Repair Products

2020 Stem Cell Therapy Market Alternative Strategies
Read more at http://www.reportsnreports.com/reports/281584-stem-cell-therapy-market-by-treatment-mode-autologous-allogeneic-therapeutic-applications-cns-cvs-...

By: paul harris

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2020 Stem Cell Therapy Market Alternative Strategies - Video

Former Ennis Coach Sam Harrell is Back Thanks to Stem Cell Therapy
Sam Harrell won three state football championships at Ennis High School, but perhaps the toughest battle he has faced has been off the field with MS. Jeff Po...

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Stem cell therapy | safety of stem cells
http://www.arthritistreatmentcenter.com So... are stem cells really safe? The answer next... Safety Of Autologous Adipose Tissue-derived Stem Cells With Platelet-rich plasma Into Human Articular...

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Research team at York University aims to improve bone disease treatment

12:45pm Friday 25th April 2014 in News By Barry Nelson, Health Editor

RESEARCHERS are aiming to develop new therapies for osteoarthritis by rejuvenating old stem cells to repair cartilage damage.

A research team at York University have been awarded 190,158 from the medical research charity Arthritis Research UK to carry out a three-year study to investigate how rejuvenated cells from older people with osteoarthritis can be used to repair worn or damaged cartilage, reducing chronic pain.

There is currently no treatment to prevent the progression of osteoarthritis, and people with severe disease often need total joint replacement surgery.

A patients own bone marrow stem cells are a valuable source of potential treatment as they can generate joint tissue that wont be rejected when re-implanted. However, as people grow older the number of stem cells decreases and those that remain are less able to grow and repair tissue.

Dr Paul Genever, lead researcher, who heads up the Arthritis Research UK Tissue Engineering Centre at the University of York said: A way to reset stem cells to an earlier time point, termed rejuvenation, has recently been discovered, allowing more effective tissue repair.

This project will firstly compare rejuvenated and non-rejuvenated stem cells to see if the process improves cartilage repair, and secondly, investigate whether it is possible to develop new drugs which are able to rejuvenate stem cells.

In the UK, more than 8m people, have sought treatment from their GP for the condition, which causes pain and stiffness in the joints due to cartilage at the ends of bones wearing away.

Professor Alan Silman, medical director at charity Arthritis Research UK, said: This is pioneering research, which has the potential to help reduce pain and disability and improving quality of life of those living with osteoarthritis.

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Research aims to improve bone disease treatment

An international team led by King's College London and the San Francisco Veteran Affairs Medical Center (SFVAMC) has developed the first lab-grown epidermis -- the outermost skin layer -- with a functional permeability barrier akin to real skin. The new epidermis, grown from human pluripotent stem cells, offers a cost-effective alternative lab model for testing drugs and cosmetics, and could also help to develop new therapies for rare and common skin disorders.

The epidermis, the outermost layer of human skin, forms a protective interface between the body and its external environment, preventing water from escaping and microbes and toxins from entering. Tissue engineers have been unable to grow epidermis with the functional barrier needed for drug testing, and have been further limited in producing an in vitro (lab) model for large-scale drug screening by the number of cells that can be grown from a single skin biopsy sample.

The new study, published in the journal Stem Cell Reports, describes the use of human induced pluripotent stem cells (iPSC) to produce an unlimited supply of pure keratinocytes -- the predominant cell type in the outermost layer of skin -- that closely match keratinocytes generated from human embryonic stem cells (hESC) and primary keratinocytes from skin biopsies. These keratinocytes were then used to manufacture 3D epidermal equivalents in a high-to-low humidity environment to build a functional permeability barrier, which is essential in protecting the body from losing moisture, and preventing the entry of chemicals, toxins and microbes.

A comparison of epidermal equivalents generated from iPSC, hESC and primary human keratinocytes (skin cells) from skin biopsies showed no significant difference in their structural or functional properties compared with the outermost layer of normal human skin.

Dr Theodora Mauro, leader of the SFVAMC team, says: "The ability to obtain an unlimited number of genetically identical units can be used to study a range of conditions where the skin's barrier is defective due to mutations in genes involved in skin barrier formation, such as ichthyosis (dry, flaky skin) or atopic dermatitis. We can use this model to study how the skin barrier develops normally, how the barrier is impaired in different diseases and how we can stimulate its repair and recovery."

Dr Dusko Ilic, leader of the team at King's College London, says: "Our new method can be used to grow much greater quantities of lab-grown human epidermal equivalents, and thus could be scaled up for commercial testing of drugs and cosmetics. Human epidermal equivalents representing different types of skin could also be grown, depending on the source of the stem cells used, and could thus be tailored to study a range of skin conditions and sensitivities in different populations."

Story Source:

The above story is based on materials provided by King's College London. Note: Materials may be edited for content and length.

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Skin layer grown from human stem cells could replace animals in drug, cosmetics testing

Treatment for Degenerative, Bulging and Herniated Discs Minimally Invasive Stem Cell Therapy
Treatment for Bulging and Herniated Discs in Thailand http://stemcellthailand.org/services-list/stem-cell-treatment-degenerative-disc-disease-back-surgery-al...

By: Regeneration Center of Thailand

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Treatment for Degenerative, Bulging and Herniated Discs Minimally Invasive Stem Cell Therapy - Video

PUBLIC RELEASE DATE:

24-Apr-2014

Contact: Jenny Gimpel jenny.gimpel@kcl.ac.uk 44-020-784-84334 King's College London

An international team led by King's College London and the San Francisco Veteran Affairs Medical Center (SFVAMC) has developed the first lab-grown epidermis the outermost skin layer - with a functional permeability barrier akin to real skin. The new epidermis, grown from human pluripotent stem cells, offers a cost-effective alternative lab model for testing drugs and cosmetics, and could also help to develop new therapies for rare and common skin disorders.

The epidermis, the outermost layer of human skin, forms a protective interface between the body and its external environment, preventing water from escaping and microbes and toxins from entering. Tissue engineers have been unable to grow epidermis with the functional barrier needed for drug testing, and have been further limited in producing an in vitro (lab) model for large-scale drug screening by the number of cells that can be grown from a single skin biopsy sample.

The new study, published in the journal Stem Cell Reports, describes the use of human induced pluripotent stem cells (iPSC) to produce an unlimited supply of pure keratinocytes the predominant cell type in the outermost layer of skin - that closely match keratinocytes generated from human embryonic stem cells (hESC) and primary keratinocytes from skin biopsies. These keratinocytes were then used to manufacture 3D epidermal equivalents in a high-to-low humidity environment to build a functional permeability barrier, which is essential in protecting the body from losing moisture, and preventing the entry of chemicals, toxins and microbes.

A comparison of epidermal equivalents generated from iPSC, hESC and primary human keratinocytes (skin cells) from skin biopsies showed no significant difference in their structural or functional properties compared with the outermost layer of normal human skin.

Dr Theodora Mauro, leader of the SFVAMC team, says: "The ability to obtain an unlimited number of genetically identical units can be used to study a range of conditions where the skin's barrier is defective due to mutations in genes involved in skin barrier formation, such as ichthyosis (dry, flaky skin) or atopic dermatitis. We can use this model to study how the skin barrier develops normally, how the barrier is impaired in different diseases and how we can stimulate its repair and recovery."

Dr Dusko Ilic, leader of the team at King's College London, says: "Our new method can be used to grow much greater quantities of lab-grown human epidermal equivalents, and thus could be scaled up for commercial testing of drugs and cosmetics. Human epidermal equivalents representing different types of skin could also be grown, depending on the source of the stem cells used, and could thus be tailored to study a range of skin conditions and sensitivities in different populations."

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Skin layer grown from human stem cells could replace animals in drug and cosmetics testing

Scientists able to produce one centimetre-wide fragments of epidermis Outer layer of skin created in a laboratory using stem cells Experts say the lab-grown skin could be used for testing lotions or creams Team from King's College London worked with scientists from the US

By Lucy Crossley

Published: 14:31 EST, 24 April 2014 | Updated: 14:42 EST, 24 April 2014

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Breakthrough: Scientists in the UK and US have been able to grow artificial skin which could replace animals in drug and cosmetics testing in a laboratory (file photo)

Artificial skin which could replace animals in drug and cosmetics testing has been grown in a laboratory for the first time.

Scientists in the UK and US were able to produce one centimetre-wide fragments of epidermis - the outermost skin layer - from stem cells with the same properties as real skin.

The epidermis forms a protective barrier between the body and external environment, preventing water from escaping while keeping out microbes and toxins.

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Artificial skin grown in laboratory for first time

More Media Coverage for MediVet Stem Cell Therapy at Newman Veterinary Centers - Central Florida
We are proud to offer this amazing procedure at Newman Veterinary Centers. Stem cell therapy can help pets with arthritis, hip dysplasia and many other degenerative conditions. Learn more at...

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More Media Coverage for MediVet Stem Cell Therapy at Newman Veterinary Centers - Central Florida - Video

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Neck/knee/shoulder/wrist pain 7 months after stem cell therapy by Dr Harry Adelson
Neck/knee/shoulder/wrist pain 7 months after stem cell therapy by Dr Harry Adelson http://www.docereclinics.com.

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PUBLIC RELEASE DATE:

23-Apr-2014

Contact: Nicanor Moldovan Moldovan.6@osu.edu 614-247-7801 Ohio State University

COLUMBUS, Ohio New research suggests that attempts to isolate an elusive adult stem cell from blood to understand and potentially improve cardiovascular health a task considered possible but very difficult might not be necessary.

Instead, scientists have found that multiple types of cells with primitive characteristics circulating in the blood appear to provide the same benefits expected from a stem cell, including the endothelial progenitor cell that is the subject of hot pursuit.

"There are people who still dream that the prototypical progenitors for several components of the cardiovascular tree will be found and isolated. I decided to focus the analysis on the whole nonpurified cell population the blood as it is," said Nicanor Moldovan, senior author of the study and a research associate professor of cardiovascular medicine at The Ohio State University.

"Our method determines the contributions of all blood cells that serve the same function that an endothelial progenitor cell is supposed to. We can detect the presence of those cells and their signatures in a clinical sample without the need to isolate them."

The study is published in the journal PLOS ONE.

Stem cells, including the still poorly understood endothelial progenitor cells, are sought-after because they have the potential to transform into many kinds of cells, suggesting that they could be used to replace damaged or missing cells as a treatment for multiple diseases.

By looking at gene activity patterns in blood, Moldovan and colleagues concluded that many cell types circulating throughout the body may protect and repair blood vessels a key to keeping the heart healthy.

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Stem cells in circulating blood affect cardiovascular health, study finds

Released: 4/21/2014 8:55 AM EDT Embargo expired: 4/23/2014 5:00 PM EDT Source Newsroom: Ohio State University Contact Information

Available for logged-in reporters only

Newswise COLUMBUS, Ohio New research suggests that attempts to isolate an elusive adult stem cell from blood to understand and potentially improve cardiovascular health a task considered possible but very difficult might not be necessary.

Instead, scientists have found that multiple types of cells with primitive characteristics circulating in the blood appear to provide the same benefits expected from a stem cell, including the endothelial progenitor cell that is the subject of hot pursuit.

There are people who still dream that the prototypical progenitors for several components of the cardiovascular tree will be found and isolated. I decided to focus the analysis on the whole nonpurified cell population the blood as it is, said Nicanor Moldovan, senior author of the study and a research associate professor of cardiovascular medicine at The Ohio State University.

Our method determines the contributions of all blood cells that serve the same function that an endothelial progenitor cell is supposed to. We can detect the presence of those cells and their signatures in a clinical sample without the need to isolate them.

The study is published in the journal PLOS ONE.

Stem cells, including the still poorly understood endothelial progenitor cells, are sought-after because they have the potential to transform into many kinds of cells, suggesting that they could be used to replace damaged or missing cells as a treatment for multiple diseases.

By looking at gene activity patterns in blood, Moldovan and colleagues concluded that many cell types circulating throughout the body may protect and repair blood vessels a key to keeping the heart healthy.

The scientists also found that several types of blood cells retain so-called primitive properties. In this context, primitive is positive because these cells are the first line of defense against an injury and provide a continuous supply of repair tissue either directly or by telling local cells what to do.

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Stem Cells in Circulating Blood Affect Cardiovascular Health

St. Petersburg, FL (PRWEB) April 23, 2014

Human Fibroblast Conditioned Media is a revolutionary ingredient that is taking the beauty and anti-aging industries by storm. These stem cells are in the Sublime Beauty "Cell Renewal | Fibroblast Serum."

These non-embryonic stem cells are rich in growth factors. When topically combined with our own skin, studies have shown that our cells are stimulated to create more collagen resulting in younger, firmer and healthier skin.

"The discovery of growth factors was a big deal in science," says Kathy Heshelow, founder of Sublime Beauty, "and plays a part in wound healing, medical applications and now skin care."

The company offers a product paper about the serum and background on its ingredients on its webstore.

The scientific anti-aging serum will be discussed on the Consumer NewsWatch TV program Thursday morning.

"Cell Renewal" is of high purity, produced under the strictest quality controls and use the latest extraction methods to capture the purest cells. This is a top of the line anti-aging treatment.

Use twice daily on cleansed skin before any other serum or cream is applied.

The company offers 25% off the serum at SublimeBeautyShop now with coupon code STEM25.

About Sublime Beauty: Sublime Beauty offers quality anti-aging skincare to "age younger". Products are available at its webstore and Amazon. The company also offers Skin Brushes and organic products.

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Improve Skin Dramatically with Stem Cell Serum, "Cell Renewal | Fibroblast Serum", from Sublime Beauty; Will Be ...

Stem Cells and Multiple Sclerosis
Dr Colin Andrews speaks about the optimistic results of treating MS (multiple sclerosis) with stem cell therapy and the ethical limitations within Australia.

By: Norwood Day Surgery

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Stem Cells and Multiple Sclerosis - Video

PUBLIC RELEASE DATE:

23-Apr-2014

Contact: Robert Miranda cogcomm@aol.com Cell Transplantation Center of Excellence for Aging and Brain Repair

Putnam Valley, NY. (Apr. 23, 2014) People who have had a stroke, often suffer motor deficits with little potential to restore neurological function. However, a study conducted in Taiwan, that will be published in a future issue of Cell Transplantation, but is currently freely available on-line as an unedited early e-pub at: http://www.ingentaconnect.com/content/cog/ct/pre-prints/content-ct1168Chen, has found that when one group of stroke victims had their own peripheral blood stem cells (PBSCs) injected directly into the brain and a similar group did not, those who received the PBSCs experienced some "improvement in stroke scales and functional outcome." Those in the PBSC-injected group also received injections of the growth factor granulocyte-colony stimulating factor (G-CSF), known to be potentially neuroprotective.

"In this phase 2 study, we provide the first evidence that intracerebral injection of autologous (self-donated) PBSCs can improve motor function in those who have suffered a stroke and have motor deficits as a result," said study corresponding Dr. Woei-Cheng Shyu of the Center for Neuropsychiatry, Graduate Institute of Immunology and Translational Medicine Research Center, China Medical University in Taiwan. "Our study demonstrated that this therapeutic strategy was feasible and safe in stroke patients who suffered a prior stroke, but within five years from the onset of symptoms."

According to the authors, there has been little advance made in restoring neurological function following ischemic stroke. However, since neuronal death is the primary mechanism that limits functional recovery, stem cell therapy is emerging as a potentially effective regenerative approach. Once more PBSCs are being increasingly used as a self-donated source for cell therapies for regenerating skeletal muscle, heart and neurons. The PBSCs may need to be "amplified" with G-CSF, speculated the researchers.

All of the patients in the trial had suffered a stroke in the past, as long as five years prior to this study. At the end of a 12 month follow-up, the group of 15 patients with neurological deficits who received injections of PBSCs experienced neurological and functional improvement based on a number of clinical outcomes measures. The control group of 15 patients with neurological deficits that did not receive the PBSC injections did not experience the same beneficial outcomes.

The researchers reported that nine of the 15 patients undergoing PBSC transplantation experienced "positive motor evoked potentials" (MEPs) after transcranial magnetic stimulation, but why MEPs appeared in some of the transplanted group, but not all, was unclear.

"Despite this success, it should be noted that this was a preliminary study and, due to the small number of patients, are tentative," concluded the researchers. "In the future we plan to conduct a multi-center, large-scale, double blind, placebo-controlled randomized studies to better evaluate the effect of PBSC implantation in patients suffering from the effects of past stroke."

"This phase II study offers pilot clinical evidence supporting the use of autologous stem cell-based treatment for stroke" said Dr. Cesar V. Borlongan, Prof. of Neurosurgery and Director of the Center of Excellence for Aging & Brain Repair at the University of South Florida. "Clarification of the impact of G-CSF on the cells and whether other factors are necessary to maximize the benefit of cell transplantation, as well as further studies with a larger number of patients are necessary to determine equivocal safety and efficacy of this treatment".

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Autologous stem cell therapy improves motor function in chronic stroke victims

Home > News > health-news

Bangalore, Apr 22 : City-based Narayana Health City (NHC) with over 300 successful Bone Marrow Transplants to its credit, today show cased the efficacy of this treatment modality with over 80 per cent success rate for curing cancerous and genetic blood diseases.

The two types of diseases which can be cured by bone marrow transplant are Leukemia, Severe Aplastic Anemia, Thassemia and Immune Deficiency Disorders.

Bone marrow transplant is a highly advanced procedure that involves transfusion of bone marrow stem cells from a healthy donor to a patient.

Speaking to reporters here, Dr Sharat Damodar, HoD and Senior Consultant Hematologist, Bone marrow transplant unit at NHC said the nature of blood diseases/disorders is either genetic in nature or acquired due to exposure to several risk factors including hazardous environment and consumption of adulterated food.

"Bone marrow transplants are now producing high success rates as it is curative in nature and offers hope to patients of a life beyond painful and fatal diseases," he said.

Dr Damodar, however, regretted that most of bone transplants are now done using bone marrow stem cells from blood relatives of the patients. "In India it is a challenge to find donors and we should consider it as our social responsibility to volunteer for donating healthy bone marrow and help patients in need," he added.

He said the government had recently opened donor registry DATRI and 50,000 people had enrolled into it.

"Compared to a population of 126 crore, we have just 50,000 donors. This is in comparison to an European country like Germany you can find millions of them," he added.

Dr Damodar and his team of experts also presented and shared the cases of patients who have been in remission for five years and leading a disease free life post bone marrow transplantation.

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NHC showcase bone marrow transplant to cure blood disorders