Oxurion Receives Transparency Notifications from Negma Group

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CLEVELAND, Feb. 03, 2023 (GLOBE NEWSWIRE) -- SPR Therapeutics, a private medical device company focused on treating pain and improving the quality of life for patients managing acute or chronic pain, announced it has obtained clearance from the U.S. Food and Drug Administration (FDA) for expanded labeling, which increases the intended patient population of the SPRINT® PNS System, along with new advances to enhance and simplify the SPRINT PNS System’s lead securement mechanism.

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SPR Therapeutics Receives 510(k) Clearance of Technological Advancements and an Expanded Intended Patient Population for the SPRINT® PNS System

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SOUTH SAN FRANCISCO, Calif. and SAN DIEGO, Feb. 03, 2023 (GLOBE NEWSWIRE) -- ORIC Pharmaceuticals, Inc. (Nasdaq: ORIC), a clinical stage oncology company focused on developing treatments that address mechanisms of therapeutic resistance, today announced that on February 1, 2023 (the “Grant Date”), ORIC granted a total of 35,596 non-qualified stock options and 5,948 restricted stock units to three new non-executive employees who began their employment with ORIC in January 2023.

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ORIC Pharmaceuticals Reports Inducement Grants under Nasdaq Listing Rule 5635(c)(4)

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NEW HAVEN, Conn., Feb. 03, 2023 (GLOBE NEWSWIRE) -- BIOASIS TECHNOLOGIES INC. (OTCQB:BIOAF; TSX.V:BTI) (the “Company” or “Bioasis”), a multi-asset rare and orphan disease biopharmaceutical company developing clinical stage programs based on epidermal growth factor and a differentiated, proprietary xB3 ™ platform for delivering therapeutics across the blood-brain barrier (“BBB”) and the treatment of central nervous system (“CNS”) disorders in areas of high unmet medical need, is pleased to announce that all resolutions were passed by the requisite majority at its annual general meeting (the “Meeting”) held earlier today.

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Basel, February 4, 2023 – Novartis announced today that The Lancet has published long-term data from the pivotal SUNSHINE and SUNRISE trials evaluating Cosentyx® (secukinumab) in moderate-to-severe hidradenitis suppurativa (HS)1. In two of the largest Phase III trials conducted in HS, Cosentyx treatment response rates continued to improve beyond the primary endpoint analysis at Week 16 to more than 55% of patients achieving a HS Clinical Response (HiSCR) measure at Week 521.

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Patients with hidradenitis suppurativa experienced sustained efficacy and symptom improvement at one year when treated with Novartis Cosentyx®

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SAN DIEGO, Feb. 03, 2023 (GLOBE NEWSWIRE) -- Sorrento Therapeutics, Inc. (Nasdaq: SRNE, “Sorrento”) today distributed dividend confirmation statements to 146 brokerage firms regarding its recent dividend to Sorrento stockholders of shares of common stock of Scilex Holding Company (Nasdaq: SCLX, “Scilex”) held by Sorrento. These statements, which contain the account numbers and amount of Scilex dividend shares, were previously mailed out by Continental Stock Transfer & Trust Company.

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Sorrento Distributes Dividend Confirmation Statements to 146 Brokerage Firms and Provides Specific Instruction to Continental Stock Transfer &...

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Vacaville high school students explore local career opportunities to honor National Career Technical Education Month Vacaville high school students explore local career opportunities to honor National Career Technical Education Month

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City of Vacaville Introduces Next Generation to Biotechnology and Advanced Manufacturing

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World's most radioactive man 'cried blood' as his skin melted in 83-day nightmare  Times Now

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How old are you, really? The answer is written on your face.  National Geographic UK

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A Possible Connection between Mild Allergic Airway Responses and Cardiovascular Risk Featured in Toxicological Sciences  Newswise

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While intrusion detection systems (IDS) monitor the network and send alerts to network administrators about potential threats, intrusion prevention systems take more substantial actions to control access to the network, monitor intrusion data, and prevent attacks from developing.

IPS evolved from IDS. IDS technology uses the same concept of identifying traffic and some of the similar techniques with the major difference being that IPS are deployed in-line and IDS are deployed off-line or on tap where they still inspect a copy of the entire traffic or flow but cannot take any preventive action. IDS are deployed to only monitor and provide analytics and visibility into the threats on the network.

Historically, IPS only reacted to cyber breaches, but this reactive stance is no longer satisfactory. IPS is now part of full network security suites, including threat monitoring, firewalls, intrusion detection, anti-virus, anti-malware, ransomware prevention, spam detection, and security analytics.

Recent trends in IPS include using AI to automate the detection process. The future of IPS technology extends network perimeter security with a multi-layered defense. Cloud IPS services perform this security function using extended detection, response, and endpoint protection.

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Advantages of IPS display panels:

If youve ever begun searching for a new computer screen, chances are youve probably come across the term IPS. Its at this point that you may be asking yourself,what is an IPS monitor?Andhow do I know if an IPS monitor is right for me?

To answer these questions we must first understand two things:

So, why is this important? A monitors panel technology is important because it affectswhat the monitor can doandfor which uses it is best suited.Each of the monitor panel types listed above offer their own distinctive benefits and drawbacks.

Choosing which type of monitor panel type to buy will depend largely on your intended usage and personal preference.After all, gamers, graphic designers, and office workers all have different requirements. Specific types of displays are best suited for different usage scenarios.

The specific type of LCD panel affects many different aspects of screen performance including:

Different panel technologies offer unique profiles with opinions on thebesttype of LCD being subjective and based on personal preference.

The reason for this is because none of the different monitor panel types as they are today can be classified as outstanding forallof the attributes mentioned above.

Below well take a look at how IPS, TN, and VA monitors affect screen performance and do some handy summaries of strengths, weaknesses, and best-case uses for each type of panel technology.

IPS monitors or In-Plane Switching monitors, leverage liquid crystals aligned in parallel to produce rich colors. IPS panels are defined by the shifting patterns of their liquid crystals. These monitors were designed to overcome the limitations of TN panels. The liquid crystals ability to shift horizontallycreates better viewing angles.

IPS monitors continue to be the display technology of choice for users that wantcolor accuracy and consistency. IPS monitors are really great when it comes tocolor performanceandsuper-wide viewing angles. The expansive viewing angles provided by IPS monitors help to deliver outstanding color when being viewed from different angles. One major differentiator between IPS monitors and TN monitors is that colors on an IPS monitor wont shift when being viewed at an angle as drastically as they do on a TN monitor.

IPS monitor variations include S-IPS, H-IPS, e-IPS and P-IPS, and PLS (Plane-to-Line Switching), the latter being the latest iteration. Since these variations are all quite similar, they are all collectively referred to as IPS-type panels. They all claim to deliver the major benefits associated with IPS monitors great color and ultra-wide viewing angles.

When it comes to color accuracy, IPS monitors surpass the performance of TN and VA monitors with ease. While latest-gen VA technologies offer comparative performance specs, pro users still claim thatIPS monitors reign supremein this regard.

Another important characteristic of IPS monitors is that they are able to support professional color space technologies, such asAdobe RGB. This is due to the fact that IPS monitors are able to offer more displayable colors, which help improve color accuracy.

In the past, response time and contrast were the initial weakness of IPS technology. Nowadays, however, IPS monitor response times have advanced to the point where they are even capable of satisfying gamers, thus resulting in a rising popularity inIPS monitors for gaming.

With regard to gaming, some criticisms IPS monitors include more visible motion blur coming as a result of slower response times, however the impact of motion blur will vary from user to user. In fact, mixed opinions about the drawbacks of IPS monitor for gaming can be found all across the web. Take this excerpt from one gaming technology writer for example: As for pixel response, opinions vary. I personally think IPS panels are quick enough for almost all gaming. If your gaming life is absolutely and exclusively about hair-trigger shooters, OK, youll want the fastest response, lowest latency LCD monitor. And that means TN. For the rest of us, and certainly for those who place even a modicum of importance on the visual spectacle of games, I reckon IPS is clearly the best panel technology. Read the full articlehere.

IPS monitors deliver ultra-wide 178-degree vertical and horizontal viewing angles. Graphic designers, CAD engineers, pro photographers, and video editors will benefit from using an IPS monitor. Many value the color benefits of IPS monitors and tech advances have improved IPS panel speed, contrast, and resolution. IPS monitors are more attractive than ever for general desktop work as well as many types of gaming. Theyre even versatile enough to be used in different monitor styles, so if youve ever compared an ultrawide vs. dual monitorsetup or considered the benefits ofcurved vs. flat monitors, chances are youve already come into contact with an IPS panel.

IPS Monitor Advantages:

IPS Monitor Drawbacks:

IPS Monitor Best Uses:

TN monitors, or Twisted Nematic monitors, are the oldest LCD panel types around. TN panels cost less than their IPS and VA counterparts and are a popular mainstream display technology for desktop and laptop displays.

Displays based on this monitor panel technology are ideal for cost-conscious consumers and entry-level multipurpose use.

Despite their lower perceived value, TN-based displays are the panel typepreferred by competitive gamers. The reason for this is because TN panels can achieve arapid response timeand thefastest refresh rates on the market(like this240Hz eSports monitor). To this effect, TN monitors are able toreduce blurring and screen tearingin fast-paced games when compared to an IPS or VA panel.

On the flip side,however, TN panel technology tends to be ill-suited for applications that benefit from wider viewing angles, higher contrast ratios, and better color accuracy. That being said, LED technology has helped shift the perspective and todays LED-backlit TN models offer higher brightness along with better blacks and higher contrast ratios.

The greatest constraint of TN panel technology, however, is a narrower viewing angle as TN monitors experience more color shifting than other types of panels when being viewed at an angle.

Todays maximum possible viewing angles are 178 degrees both horizontally and vertically (178/178), yet TN panels are limited to viewing angles of approximately 170 degrees horizontal and 160 degrees vertical (170 /160).

In fact, TN monitor can sometimes be easily identified by the color distortion and contrast shifting thats visible at the edges of the screen. As screen sizes increase, this issue becomes even more apparent as reduced color performance can even begin to be seen when viewing the screen from a dead-center position.

For general-purpose use, these shifts in color and contrast are often irrelevant and fade from conscious perception. However, this color variability makes TN monitors a poor choice for color-critical work like graphic design and photo editing. Graphic designers and other color-conscious users should also avoid TN displays due to their more limited range of color display compared to the other technologies.

TN monitors are the least expensive panel technology, making them ideal for cost-conscious businesses and consumers. In addition, TN monitors enjoy unmatched popularity with competitive gamers and other users who seek rapid graphics display.

TN Monitor Advantages:

TN Monitor Drawbacks:

TN Monitor Best Uses:

Vertical alignment (VA) panel technology was developed to improve upon the drawbacks of TN. Current VA-based monitors offer much higher contrast, better color reproduction, and wider viewing angles than TN panels. Variations you may see include P-MVA, S-MVA, and AMVA (Advanced MVA).

These high-end VA-type monitors rival IPS monitors as the best panel technology for professional-level color-critical applications. One of the standout features of VA technology is that it is particularly good at blocking light from the backlight when its not needed. This enables VA panels to display deeper blacks and static contrast ratios of up to several times higher than the other LCD technologies. The benefit of this is that VA monitors with high contrast ratios can deliver intense blacks and richer colors.

Contrast ratio is themeasured difference between the darkest blacks and the brightest whites a monitor can produce. This measurement provides information about the amount of grayscale detail a monitor will deliver. The higher the contrast ratio, the more visible detail.

These monitors also provide more visible details in shadows and highlights, making them ideal for enjoying videos and movies. Theyre also a good fit for games focused on rich imagery (RPG games for example) rather than rapid speed (such as FPS games).

MVA and other recent VA technologies offer the highest static contrast ratios of any panel technology. This allows for an outstanding visual experience for movie enthusiasts and other users seeking depth of detail. Higher-end, feature-rich MVA displays offer the consistent, authentic color representation needed by graphic designers and other pro users.

VA Monitor Advantages:

VA Monitor Drawbacks:

VA Monitor Best uses:

How does OLED compare to LCD?

There is another type of panel technology that differs from the monitor types discussed above and that is OLED or Organic Light Emitting Diode technology. OLEDs differ from LCDs because they use positively/negatively charged ions to light up every pixel individually, while LCDs use a backlight, which can create an unwanted glow. OLEDs avoid screen glow (and create darker blacks) by not using a backlight. One of the drawbacks of OLED technology is that it is usually pricier than any of the other types of technology explained.

Choosing the Right LCD Panel Technology

When it comes to choosing the right LCD panel technology, there is no single right answer. Each of the three primary technologies offers distinct strengths and weaknesses. Looking at different features and specs helps you identify which monitor best fits your needs.

With the lowest cost and fastest response times, TN monitors are great for general use and gaming. VA monitor offers a step up for general use. Maxed-out viewing angles and high contrast ratios make VA monitors great for watching movies and image-intensive gaming.

IPS monitors offer the greatest range of color-related features and remain the gold standard for photo editing and color-critical pro uses. Greater availability and lower prices make IPS monitors a great fit for anyone who values outstanding image quality.

LCD or Liquid Crystal Display is a type of monitor panel that embraces thin layers of liquid crystals sandwiched between two layers of filters and electrodes.

While CRT monitors used to fire electrons against glass surfaces, LCD monitors operate using backlights and liquid crystals. The LCD panel is a flat sheet of material that contains layers of filters, glass, electrodes, liquid crystals, and a backlight. Polarized light (meaning only half of it shines through) is directed towards a rectangular grid of liquid crystals and beamed through.

Liquid Crystals (LCs) are used because of their unique ability to maintain a parallel shape. Acting as both a solid and liquid, LCs are able to react quickly to changes in light patterns. The optical properties of LCs are activated by electric current, which is used to switch liquid crystals between phases. In turn, each pixel generates an RGB (red, green, blue) color based on the phase its in.

Note: When searching for monitors you can be sure to come across the term LED Panel at some point or another. An LED panel is an LCD screen with an LED (Light Emitting Diode) backlight. LEDs provide a brighter light source while using much less energy. They also have the ability to produce white color, in addition to traditional RGB color, and are the panel type used in HDR monitors.

Early LCD panels usedpassive-matrix technologyand were criticized for blurry imagery. The reason for this is because quick image changes require liquid crystals to change phase quickly and passive matrix technology was limited in terms of how quickly liquid crystals could change phase.

As a result,active-matrix technologywas invented andtransistors(TFTs) began being used to help liquid crystals retain their charge and change phase more quickly.

Thanks to active-matrix technology,LCD monitor panels were able to change images very quickly and the technology began being used by newer LCD panels.

Ultimately, budget and feature preferences will determine the best fit for each user. Among the available monitors of each panel type there will also be a range of price points and feature sets. Additionally, overall quality may vary among manufacturers due to factors related to a displays components, manufacturing, and design.

If youre interested in learning more about IPS monitors, you can take a look at some of theseprofessional monitorsto see if they would be the right fit for you.

Alternatively, if youre into gaming and are in the market for TN panel thesegaming monitoroptions may be along the lines of what youre looking for.

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IPS (in-plane switching) is a screen technology for liquid-crystal displays (LCDs). In IPS, a layer of liquid crystals is sandwiched between two glass surfaces. The liquid crystal molecules are aligned parallel to those surfaces in predetermined directions (in-plane). The molecules are reoriented by an applied electric field, whilst remaining essentially parallel to the surfaces to produce an image. It was designed to solve the strong viewing angle dependence and low-quality color reproduction of the twisted nematic field effect (TN) matrix LCDs prevalent in the late 1980s.[1]

The TN method was the only viable technology for active matrix TFT LCDs in the late 1980s and early 1990s. Early panels showed grayscale inversion from up to down,[2] and had a high response time (for this kind of transition, 1ms is visually better than 5ms). In the mid-1990s new technologies were developedtypically IPS and Vertical Alignment (VA)that could resolve these weaknesses and were applied to large computer monitor panels.

One approach patented in 1974 was to use inter-digitated electrodes on one glass substrate only to produce an electric field essentially parallel to the glass substrates.[3][4] However, the inventor was not yet able to implement such IPS-LCDs superior to TN displays.

After thorough analysis, details of advantageous molecular arrangements were filed in Germany by Guenter Baur et al. and patented in various countries including the US on 9 January 1990.[5][6] The Fraunhofer Society in Freiburg, where the inventors worked, assigned these patents to Merck KGaA, Darmstadt, Germany.

Shortly thereafter, Hitachi of Japan filed patents to improve this technology. A leader in this field was Katsumi Kondo, who worked at the Hitachi Research Center.[7] In 1992, engineers at Hitachi worked out various practical details of the IPS technology to interconnect the thin-film transistor array as a matrix and to avoid undesirable stray fields in between pixels.[8][9] Hitachi also improved the viewing angle dependence further by optimizing the shape of the electrodes (Super IPS). NEC and Hitachi became early manufacturers of active-matrix addressed LCDs based on the IPS technology. This is a milestone for implementing large-screen LCDs having acceptable visual performance for flat-panel computer monitors and television screens. In 1996, Samsung developed the optical patterning technique that enables multi-domain LCD. Multi-domain and in-plane switching subsequently remain the dominant LCD designs through 2006.[10]

Later, LG Display and other South Korean, Japanese, and Taiwanese LCD manufacturers adapted IPS technology.

IPS technology is widely used in panels for TVs, tablet computers, and smartphones. In particular, most IBM products was marketed as Flexview from 2004 to 2008 has an IPS LCDs with CCFL backlighting, and all Apple Inc. products marketed with the label Retina Display[11][12] feature IPS LCDs with LED backlighting since 2010.

In this case, both linear polarizing filters P and A have their axes of transmission in the same direction. To obtain the 90 degree twisted nematic structure of the LC layer between the two glass plates without an applied electric field (OFF state), the inner surfaces of the glass plates are treated to align the bordering LC molecules at a right angle. This molecular structure is practically the same as in TN LCDs. However, the arrangement of the electrodes e1 and e2 is different. Because they are in the same plane and on a single glass plate, they generate an electric field essentially parallel to this plate. The diagram is not to scale: the LC layer is only a few micrometers thick and so is very small compared with the distance between the electrodes.

The LC molecules have a positive dielectric anisotropy and align themselves with their long axis parallel to an applied electrical field. In the OFF state (shown on the left), entering light L1 becomes linearly polarized by polarizer P. The twisted nematic LC layer rotates the polarization axis of the passing light by 90 degrees, so that ideally no light passes through polarizer A. In the ON state, a sufficient voltage is applied between electrodes and a corresponding electrical field E is generated that realigns the LC molecules as shown on the right of the diagram. Here, light L2 can pass through polarizer A.

In practice, other schemes of implementation exist with a different structure of the LC molecules for example without any twist in the OFF state. As both electrodes are on the same substrate, they take more space than TN matrix electrodes. This also reduces contrast and brightness.[16]

Super-IPS was later introduced with better response times and colour reproduction.[17][unreliable source?]

Toward the end of 2010 Samsung Electronics introduced Super PLS (Plane-to-Line Switching) with the intent of providing an alternative to the popular IPS technology which is primarily manufactured by LG Display. It is an "IPS-type" panel technology, and is very similar in performance features, specs and characteristics to LG Display's offering. Samsung adopted PLS panels instead of AMOLED panels, because in the past AMOLED panels had difficulties in realizing full HD resolution on mobile devices. PLS technology was Samsung's wide-viewing angle LCD technology, similar to LG Display's IPS technology.[24]

Samsung asserted the following benefits of Super PLS (commonly referred to as just "PLS") over IPS:[25]

In 2012 AU Optronics began investment in their own IPS-type technology, dubbed AHVA. This should not be confused with their long standing AMVA technology (which is a VA-type technology). Performance and specs remained very similar to LG Display's IPS and Samsung's PLS offerings. The first 144Hz compatible IPS-type panels were produced in late 2014 (used first in early 2015) by AUO, beating Samsung and LG Display to providing high refresh rate IPS-type panels.[26][27]

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Bone health: Tips to keep your bones healthy

Protecting your bone health is easier than you think. Understand how diet, physical activity and other lifestyle factors can affect your bone mass.

Bones play many roles in the body providing structure, protecting organs, anchoring muscles and storing calcium. While it's important to build strong and healthy bones during childhood and adolescence, you can take steps during adulthood to protect bone health, too.

Your bones are continuously changing new bone is made and old bone is broken down. When you're young, your body makes new bone faster than it breaks down old bone, and your bone mass increases. Most people reach their peak bone mass around age 30. After that, bone remodeling continues, but you lose slightly more bone mass than you gain.

How likely you are to develop osteoporosis a condition that causes bones to become weak and brittle depends on how much bone mass you attain by the time you reach age 30 and how rapidly you lose it after that. The higher your peak bone mass, the more bone you have "in the bank" and the less likely you are to develop osteoporosis as you age.

A number of factors can affect bone health. For example:

You can take a few simple steps to prevent or slow bone loss. For example:

Include plenty of calcium in your diet. For adults ages 19 to 50 and men ages 51 to 70, the Recommended Dietary Allowance (RDA) is 1,000 milligrams (mg) of calcium a day. The recommendation increases to 1,200 mg a day for women age 51 and older and for men age 71 and older.

Good sources of calcium include dairy products, almonds, broccoli, kale, canned salmon with bones, sardines and soy products, such as tofu. If you find it difficult to get enough calcium from your diet, ask your doctor about supplements.

Pay attention to vitamin D. Your body needs vitamin D to absorb calcium. For adults ages 19 to 70, the RDA of vitamin D is 600 international units (IUs) a day. The recommendation increases to 800 IUs a day for adults age 71 and older.

Good sources of vitamin D include oily fish, such as salmon, trout, whitefish and tuna. Additionally, mushrooms, eggs and fortified foods, such as milk and cereals, are good sources of vitamin D. Sunlight also contributes to the body's production of vitamin D. If you're worried about getting enough vitamin D, ask your doctor about supplements.

If you're concerned about your bone health or your risk factors for osteoporosis, including a recent bone fracture, consult your doctor. He or she might recommend a bone density test. The results will help your doctor gauge your bone density and determine your rate of bone loss. By evaluating this information and your risk factors, your doctor can assess whether you might be a candidate for medication to help slow bone loss.

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Overview

Bone cancer can begin in any bone in the body, but it most commonly affects the pelvis or the long bones in the arms and legs. Bone cancer is rare, making up less than 1 percent of all cancers. In fact, noncancerous bone tumors are much more common than cancerous ones.

The term "bone cancer" doesn't include cancers that begin elsewhere in the body and spread (metastasize) to the bone. Instead, those cancers are named for where they began, such as breast cancer that has metastasized to the bone.

Some types of bone cancer occur primarily in children, while others affect mostly adults. Surgical removal is the most common treatment, but chemotherapy and radiation therapy also may be utilized. The decision to use surgery, chemotherapy or radiation therapy is based on the type of bone cancer being treated.

Signs and symptoms of bone cancer include:

Make an appointment with your doctor if you or your child develops bone pain that:

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The cause of most bone cancers is unknown. A small number of bone cancers have been linked to hereditary factors, while others are related to previous radiation exposure.

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Osteosarcoma, the most common type of bone cancer, often starts in the long bones the legs or the arms but it can occur in any bone.

Bone cancers are broken down into separate types based on the type of cell where the cancer began. The most common types of bone cancer include:

It's not clear what causes bone cancer, but doctors have found certain factors are associated with an increased risk, including:

Bone cancer care at Mayo Clinic

March 22, 2022

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Karina Hernandez, a nurse, mother and wife of a military officer, was diagnosed with cancer.

SAN ANTONIO A bone marrow registry was held Sunday for the wife of an Air Force Major stationed here in San Antonio.

Karina Hernandez, a nurse at BAMC, mother and wife of a military officer, was diagnosed with a rare bone marrow cancer called Myelofibrosis back in 2017 while pregnant.

She had severe pain in her side that wouldn't go away. Testing revealed that not only was she pregnant, she had an enlarged spleen due to Myelofibrosis.

We spoke with her awesome husband, Major Jesse Hernandez on Sunday about the challenges they have faced.

"Her cancer has progressed to the point where she know requires a bone marrow transplant in order to save her life," said Major Hernandez. "So today we're running a bone marrow registry drive with the goal to find a match for my wife and maybe for other patients who are facing the same need."

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There are over 18,000 patients that could benefit from healthy bone marrow and it could save their life.

"Karina continues to work at BAMC caring for other people, all while battling cancer," said Major Hernandez. "She has been on chemo medications the whole time and this is my opportunity to try and help her and hopefully find someone who is a match to help her."

Her friends and family all say Karina cares more about getting people to sign up for the registry to help others.

She is concerned that - It's not just for herself, it's for how many other people can be helped by this, said Dora Lopez, one of the drives organizers.

Unfortunately, Hispanics do not commonly sign themselves up as donors, said her family. So it has been difficult to try and find a match for her.

"The chances of a Caucasian patient finding a matches is 79% Hispanics is a 48% chance and African Americans is only a 29% chance," said Be The Match Recruitment Coordinator Melinda Dixon.

A bone marrow registry in her honor was held Sunday at St. Anthony Mary Claret Catholic Church located at 6150 Roft Road from 7 a.m. to 7 p.m.

If you missed the drive, you can still sign up for the registry by following this link or by texting Cure4Karina to 61474.

You must be at least 18 years old to register. You will not be asked to donate right away, only to swab the inside of your cheeks to send in so your DNA can be added to the national registry. if it is a match for a patient, a donation could save a life.

Since going on the air in 1950, KENS 5has strived to be the best, most trusted news and entertainment source for generations of San Antonians.

KENS 5 has brought numerous firsts to South Texas television, including being the first local station with a helicopter, the first with its own Doppler radar and the first to air a local morning news program.

Over the years, KENS 5 has worked to transform local news. Our cameras have been the lens bringing history into local viewers' homes. We're proud of our legacy as we serve San Antonians today.

Today, KENS 5 continues to set the standard in local broadcasting and is recognized by its peers for excellence and innovation. The KENS 5 News team focuses on stories that really matter to our community.

You can find KENS 5 in more places than ever before, including KENS5.com, the KENS 5 app, the KENS 5 YouTube channel, KENS 5's Roku and Fire TV apps, and across social media on Facebook, Twitter, Instagram and more!

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Overview The three layers of skin on top of muscle tissue.What is the skin?

The skin is the bodys largest organ, made of water, protein, fats and minerals. Your skin protects your body from germs and regulates body temperature. Nerves in the skin help you feel sensations like hot and cold.

Your skin, along with your hair, nails, oil glands and sweat glands, is part of the integumentary (in-TEG-you-MEINT-a-ree) system. Integumentary means a bodys outer covering.

Three layers of tissue make up the skin:

Your epidermis is the top layer of the skin that you can see and touch. Keratin, a protein inside skin cells, makes up the skin cells and, along with other proteins, sticks together to form this layer. The epidermis:

The dermis makes up 90% of skins thickness. This middle layer of skin:

The bottom layer of skin, or hypodermis, is the fatty layer. The hypodermis:

One inch of your skin has approximately 19 million skin cells and 60,000 melanocytes (cells that make melanin or skin pigment). It also contains 1,000 nerve endings and 20 blood vessels.

As the bodys external protection system, your skin is at risk for various problems. These include:

You lose collagen and elastin as you age. This causes the skins middle layer (dermis) to get thinner. As a result, the skin may sag and develop wrinkles.

While you cant stop the aging process, these actions can help maintain healthier skin:

You should call your healthcare provider if you experience:

A note from Cleveland Clinic

As the bodys largest organ, your skin plays a vital role in protecting your body from germs and the elements. It keeps your body at a comfortable temperature, and nerves beneath the skin provide the sense of touch. This external body covering can have serious problems like skin cancer, as well as more common issues like acne and skin rashes. Your healthcare provider can offer tips to help keep skin healthy.

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Skin: Layers, Structure and Function - Cleveland Clinic

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Skin disorders vary greatly in symptoms and severity. They can be temporary or permanent and may be painless or painful. Some skin conditions are minor, and others can be life threatening.

Some skin disorders have situational causes, while others may be genetic. While most skin disorders are minor, others can indicate a more serious issue.

Contact a doctor if you believe you may have one of these common skin problems.

There are many different types of skin disorders. Here are pictures of 25 different conditions, followed by a list of details for each.

Learn more about acne.

Learn more about cold sores and cold sores on dark skin.

Learn more about blisters.

Learn more about hives.

Learn more about actinic keratosis.

Learn more about rosacea.

Learn more about carbuncles.

This condition is considered a medical emergency. Urgent care may be required. Contact 911 or local emergency services.

Learn more about latex allergies.

Learn more about eczema.

Learn more about psoriasis.

Cellulitis is a medical emergency. A person should contact 911 or local emergency services if they have any symptoms of cellulitis.

Learn more about cellulitis.

Learn more about measles.

Learn more about basal cell carcinoma.

Learn more about squamous cell carcinoma.

Learn more about melanoma.

Learn more about lupus.

Learn more about contact dermatitis.

Learn more about vitiligo.

Learn more about warts.

Learn more about chickenpox.

Learn more about seborrheic eczema.

Learn more about keratosis pilaris.

Learn more about ringworm.

Learn more about melasma.

Learn more about impetigo.

Contact dermatitis is one of the most common occupational illnesses, often resulting from contact with chemicals or other irritating materials.

These substances can trigger a reaction that causes the skin to become itchy and inflamed. Affected areas might also appear red, purple, gray, or dark brown. Most cases of contact dermatitis arent severe, but they can be rather itchy.

Topical creams and avoiding the irritant are typical treatments.

Keratosis pilaris is a minor condition that causes small, rough bumps on the skin. These bumps usually form on the upper arms, thighs, or cheeks. Theyre typically red or white and dont hurt or itch.

Treatment isnt necessary, but medicated creams can improve skin appearance.

Some chronic skin conditions present from birth, while others appear suddenly later.

The cause of these disorders isnt always known. Many permanent skin disorders have effective treatments that enable extended periods of remission. However, theyre incurable, and symptoms can reappear at any time.

Examples of chronic skin conditions include:

Skin disorders are common in children. Children can experience many of the same skin conditions as adults. Infants and toddlers are also at risk of diaper-related skin problems.

Since children have more frequent exposure to other children and germs, they may also develop skin disorders that rarely occur in adults.

Many childhood skin problems disappear with age, but children can also inherit permanent skin disorders. In most cases, doctors can treat childhood skin disorders with topical creams, medicated lotions, or condition-specific drugs.

Common childhood skin disorders include:

Skin conditions have a wide range of symptoms. Symptoms on your skin that appear due to common problems arent always the result of a skin disorder. Such symptoms can include blisters from new shoes or chafing from tight pants.

However, skin problems with no obvious cause may indicate the presence of a skin disorder that requires treatment.

Skin irregularities that are typically symptoms of a skin disorder include:

Common known causes of skin disorders include:

Numerous health conditions and lifestyle factors can also lead to the development of certain skin disorders. Some skin conditions have no known cause.

Inflammatory bowel disease is a term for a group of intestinal disorders that cause prolonged inflammation of the digestive tract. These bowel-related disorders often cause skin problems.

The drugs used to treat these diseases can cause certain skin conditions, such as:

Many people with diabetes experience a skin problem due to their condition at some point.

Some of these skin disorders only affect people with diabetes. Others occur more frequently in people with diabetes because the disease increases the risk of infection and blood circulation problems.

Diabetes-related skin conditions include:

Lupus is a chronic inflammatory disease that can damage the skin, joints, or organs inside the body. Common skin problems that occur from lupus include:

Pregnancy causes significant changes in hormone levels that may lead to skin problems. Preexisting skin problems may change or get worse during pregnancy. Most skin conditions that arise during pregnancy go away after the baby is born. Others require medical attention during pregnancy.

Common skin conditions caused by pregnancy include:

Stress can cause hormonal imbalances, which may trigger or aggravate skin disorders. Stress-related skin problems include:

The sun can cause many different skin disorders. Some are common and harmless, while others are rare or life threatening. Knowing if the sun causes or worsens your skin disorder is important for treating it properly.

Sunlight exposure may cause or aggravate the following conditions:

Many skin disorders are treatable. Common treatment methods for skin conditions include:

Not all skin disorders respond to treatment, and some conditions go away without treatment.

People with permanent skin conditions often go through periods of severe symptoms. Sometimes people are able to force incurable conditions into remission. However, most skin conditions reappear due to certain triggers, such as stress or illness.

You can often treat skin disorders that are temporary and cosmetic with:

Certain skin disorders arent preventable, including genetic conditions and some skin problems due to other illnesses. However, its possible to prevent some skin disorders.

Follow these tips to prevent infectious skin disorders:

Noninfectious skin disorders, such as acne and atopic dermatitis, are sometimes preventable. Prevention techniques vary depending on the condition. Here are some tips for preventing some noninfectious skin disorders:

Learning about proper skin care and treatment for skin disorders can be very important for skin health. Some conditions require a doctors attention, while you can address others safely at home.

You should learn about your symptoms or condition and talk with a doctor to determine the best treatment methods.

According to the American Academy of Dermatology Association, acne is the most common skin condition in the United States. Other common skin disorders include atopic dermatitis, hair loss, and rosacea.

There are several serious skin conditions. In particular, melanoma is a type of skin cancer that can be especially dangerous, as it could spread to other parts of the body if not caught early. Cellulitis and latex allergy can also be very serious if left untreated.

A few examples of chronic skin conditions include rosacea, psoriasis, and vitiligo. While these conditions cant be cured, some may have treatments available to help manage symptoms.

Different types of conditions affect the skin. Some are chronic, while others are temporary. Some conditions may be painful or uncomfortable, but theyre not dangerous. Other conditions, such as skin cancer, can be life threatening.

The treatment for each depends on the specific cause. If you experience any new or unusual skin symptoms, its a good idea to have them evaluated by a doctor.

Read this article in Spanish.

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Skin Disorders: Pictures, Causes, Symptoms, and Treatment - Healthline

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Summary

human skin, in human anatomy, the covering, or integument, of the bodys surface that both provides protection and receives sensory stimuli from the external environment. The skin consists of three layers of tissue: the epidermis, an outermost layer that contains the primary protective structure, the stratum corneum; the dermis, a fibrous layer that supports and strengthens the epidermis; and the subcutis, a subcutaneous layer of fat beneath the dermis that supplies nutrients to the other two layers and that cushions and insulates the body.

The apparent lack of body hair immediately distinguishes human beings from all other large land mammals. Regardless of individual or racial differences, the human body seems to be more or less hairless, in the sense that the hair is so vestigial as to seem absent; yet in certain areas hair grows profusely. These relatively hairy places may be referred to as epigamic areas, and they are concerned with social and sexual communication, either visually or by scent from glands associated with the hair follicles.

The characteristic features of skin change from the time of birth to old age. In infants and children it is velvety, dry, soft, and largely free of wrinkles and blemishes. Children younger than two years sweat poorly and irregularly; their sebaceous glands function minimally. At adolescence hair becomes longer, thicker, and more pigmented, particularly in the scalp, axillae, pubic eminence, and the male face. General skin pigmentation increases, localized pigmented foci appear mysteriously, and acne lesions often develop. Hair growth, sweating, and sebaceous secretion begin to blossom. As a person ages, anatomical and physiological alterations, as well as exposure to sunlight and wind, leave skin, particularly that not protected by clothing, dry, wrinkled, and flaccid.

Human skin, more than that of any other mammal, exhibits striking topographic differences. An example is the dissimilarity between the palms and the backs of the hands and fingers. The skin of the eyebrows is thick, coarse, and hairy; that on the eyelids is thin, smooth, and covered with almost invisible hairs. The face is seldom visibly haired on the forehead and cheekbones. It is completely hairless in the vermilion border of the lips, yet coarsely hairy over the chin and jaws of males. The surfaces of the forehead, cheeks, and nose are normally oily, in contrast with the relatively greaseless lower surface of the chin and jaws. The skin of the chest, pubic region, scalp, axillae, abdomen, soles of the feet, and ends of the fingers varies as much structurally and functionally as it would if the skin in these different areas belonged to different animals.

The skin achieves strength and pliability by being composed of numbers of layers oriented so that each complements the others structurally and functionally. To allow communication with the environment, countless nervessome modified as specialized receptor end organs and others more or less structurelesscome as close as possible to the surface layer, and nearly every skin organ is enwrapped by skeins of fine sensory nerves.

The dermis makes up the bulk of the skin and provides physical protection. It is composed of an association of fibres, mainly collagen, with materials known as glycosaminoglycans, which are capable of holding a large amount of water, thus maintaining the turgidity of the skin. A network of extendable elastic fibres keeps the skin taut and restores it after it has been stretched.

The hair follicles and skin glands are derived from the epidermis but are deeply embedded in the dermis. The dermis is richly supplied with blood vessels, although none penetrates the living epidermis. The epidermis receives materials only by diffusion from below. The dermis also contains nerves and sense organs at various levels.

Human skin is enormously well supplied with blood vessels; it is pervaded with a tangled, though apparently orderly, mass of arteries, veins, and capillaries. Such a supply of blood, far in excess of the maximum biologic needs of the skin itself, is evidence that the skin is at the service of the blood vascular system, functioning as a cooling device. To aid in this function, sweat glands pour water upon its surface, the evaporation of which absorbs heat from the skin. If the environment is cold and body heat must be conserved, cutaneous blood vessels contract in quick, successive rhythms, allowing only a small amount of blood to flow through them. When the environment is warm, they contract at long intervals, providing a free flow of blood. During muscular exertion, when great quantities of generated heat must be dissipated, blood flow through the skin is maximal.

In addition to its control of body temperature, skin also plays a role in the regulation of blood pressure. Much of the flow of blood can be controlled by the opening and closing of certain sphincterlike vessels in the skin. These vessels allow the blood to circulate through the peripheral capillary beds or to bypass them by being shunted directly from small arteries to veins.

Human skin is permeated with an intricate mesh of lymph vessels. In the more superficial parts of the dermis, minute lymph vessels that appear to terminate in blind sacs function as affluents of a superficial lymphatic net that in turn opens into vessels that become progressively larger in the deeper portions of the dermis. The deeper, larger vessels are embedded in the loose connective tissue that surrounds the veins. The walls of lymph vessels are so flabby and collapsed that they often escape notice in specimens prepared for microscopic studies. Their abundance, however, has been demonstrated by injecting vital dyes inside the dermis and observing the clearance of the dye.

Because lymph vessels have minimal or no musculature in their walls, the circulation of lymph is sluggish and largely controlled by such extrinsic forces as pressure, skeletal muscle action, massaging, and heat. Any external pressure exerted, even from a fixed dressing, for example, interferes with its flow. Since skin plays a major role in immunologic responses of the body, its lymphatic drainage is as significant as its blood vascular system.

The intact surface of the skin is pitted by the orifices of sweat glands and hair folliclesthe so-called poresand is furrowed by intersecting lines that delineate characteristic patterns. All individuals have roughly similar markings on any one part of the body, but the details are unique. The lines are oriented in the general direction of elastic tension. Countless numbers of them, deep and shallow, together with the pores, give every region of the body a characteristic topography. Like the deeper furrows and ridges on the palms and soles, the skin lines are mostly established before birth. The fine details of each area of body surface are peculiar to each individual. Fingerprints are used as a means of personal identification because they have a high relief, more evident patternings, and can be easily obtained.

Some of the lines on the surface of the skin are acquired after birth as a result of use or damage. For example, furrows on the forehead are an accentuation of preexisting congenital lines that become strongly emphasized in old age. As the skin becomes less firm with aging, it also forms wrinkles. Certain occupations leave skin marks that, depending upon duration and severity, may be transient or permanent.

The palms of the hands and the soles of the feet are etched by distinct alternating ridges and grooves that together constitute dermatoglyphics. The ridges follow variable courses, but their arrangement in specific areas has a consistent structural plan. Though apparently continuous, the ridges have many interruptions and irregularities, branching and varying in length. Every small area of surface has ridge details not matched anywhere in the same individual or in any other individual, even in an identical twin. This infallible signature makes dermatoglyphics the best-known physical characteristic for personal identification.

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Human skin | Definition, Layers, Types, & Facts | Britannica

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Cynthias story

Cynthia had always been proud of her skin, especially her summer tan. But, as years went by, she saw her skin getting more fine lines and wrinkles. Cynthia began to worry about what other skin problems she might have. What were those brown spots on her hands and arms?

Your skin changes with age. It becomes thinner, loses fat, and no longer looks as plump and smooth as it once did. Your veins and bones can be seen more easily. Scratches, cuts, or bumps can take longer to heal. Years of suntanning or being out in the sunlight for a long time may lead to wrinkles, dryness, age spots, and even cancer. But there are things you can do to protect your skin and to make it feel and look better.

Many older people suffer from dry spots on their skin, often on their lower legs, elbows, and lower arms. Dry skin patches feel rough and scaly. There are many possible reasons for dry skin, such as:

Dry skin also can be caused by health problems, such as diabetes or kidney disease. Using too much soap, antiperspirant, or perfume and taking hot baths can make dry skin worse.

Some medicines can make skin itchy. Because older people have thinner skin, scratching can cause bleeding that may lead to infection. Talk to your doctor if your skin is very dry and itchy.

Here are some ways to help dry, itchy skin:

Older people may bruise more easily than younger people. It can take longer for these bruises to heal. Some medicines or illnesses may also cause bruising. Talk to your doctor if you see bruises and dont know how you got them, especially on parts of your body usually covered by clothing.

Over time, skin begins to wrinkle. Things in the environment, like ultraviolet (UV) light from the sun, can make the skin less elastic. Gravity can cause skin to sag and wrinkle. Certain habits, like smoking, also can wrinkle the skin.

A lot of claims are made about ways to make wrinkles go away. Most of them dont work. Some methods can be painful or even dangerous, and many must be done by a doctor. Talk with a doctor specially trained in skin problems, called a dermatologist, or your regular doctor if you are worried about wrinkles.

Age spots, once called liver spots, are flat, brown spots often caused by years in the sun. They are bigger than freckles and commonly show up on areas like the face, hands, arms, back, and feet. Using a broad-spectrum sunscreen that helps protect against two types of the suns rays (UVA and UVB) may prevent more age spots.

Skin tags are small, usually flesh-colored growths of skin that have a raised surface. They become common as people age, especially for women. They are most often found on the eyelids, neck, and body folds such as the armpit, chest, and groin.

Age spots and skin tags are harmless, although sometimes skin tags can become irritated. If your age spots or skin tags bother you, talk to your doctor about having them removed.

Skin cancer is a very common type of cancer in the United States. The main cause of skin cancer is the sun. Sunlamps and tanning booths can also cause skin cancer. Anyone, of any skin color, can get skin cancer. People with fair skin that freckles easily are at greatest risk. Skin cancer may be cured if it is found before it spreads to other parts of the body.

There are three types of skin cancers. Two types, basal cell carcinoma and squamous cell carcinoma, grow slowly and rarely spread to other parts of the body. These types of cancer are usually found on parts of the skin most often exposed to the sun, like the head, face, neck, hands, and arms. But they can happen anywhere on your body. The third and most dangerous type of skin cancer is melanoma. It is rarer than the other types, but it can spread to other organs and be deadly.

Check your skin once a month for things that may be signs of cancer. Skin cancer is rarely painful. Look for changes such as a new growth, a sore that doesnt heal, or a bleeding mole.

A = Asymmetry (one half of the growth looks different from the other half)

B = Borders that are irregular

C = Color changes or more than one color

D = Diameter greater than the size of a pencil eraser

E = Evolving; meaning the growth changes in size, shape, symptoms (itching, tenderness), surface (especially bleeding), or shades of color

See your doctor right away if you have any of these signs to make sure it is not skin cancer.

Some sun can be good for you, but to keep your skin healthy, be careful:

Your skin may change with age. But remember, there are things you can do to help. Check your skin often. If you find any changes that worry you, see your doctor.

Read about this topic in Spanish. Lea sobre este tema en espaol.

This content is provided by the NIH National Institute on Aging (NIA). NIA scientists and other experts review this content to ensure it is accurate and up to date.

Content reviewed: October 01, 2017

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Skin Care and Aging | National Institute on Aging

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