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Researchers Home in on Biological Ways to Restore Hearing [Excerpt]

By Dr. Matthew Watson

Editor’s Note: Excerpted from Shouting Won’t Help: Why I--and 50 Million Other Americans--Can’t Hear You , by Katherine Bouton, published by Sarah Crichton Books, an imprint of Farrar, Straus and Giroux, LLC. Copyright © 2013 Katherine Bouton. All rights reserved.

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Cyberspace Makeover at California Stem Cell Agency

By Dr. Matthew Watson

California's $3 billion stem cell
agency has performed a well-done makeover on its most important
public face – its web site, which is chock-a-block full of useful
information for researchers and the unwashed alike.

At cirm.ca.gov, one can find the very
words of its directors as they wrestle with everything from grant
approvals to conflicts of interest. Scientists can be seen telling
the story of their accomplishments. Money can be followed, and
summaries of reviews of grant applications read, both those approved
and those that did not pass muster.
The web site of the California
Institute of Regenerative Medicine
 (the formal name of the agency) is the place where the stem cell program
really meets the public. News stories are important, but infrequent.
Day to day, however, thousands of interested persons seek out
information that the folks at CIRM HQ, just a long throw from the San
Francisco Giants
ballpark, bring to cyberspace.
Each month, said Amy Adams, major domo
of the web site, 15,000 to 17,000 “unique viewers”
visit online. She told the California Stem Cell
Report
in an email,

“We're up about 25 percent year over
year in unique viewers to the site. A lot of that growth comes from
search, and the rest is from traffic driven through our blog and
Facebook.” 

The numbers are not huge compared to
those chalked up by major media sites. But they are significant
given that there are only a few thousand people worldwide who are
deeply and regularly interested in stem cell research. Many more,
however, are stimulated to look into the subject from time to time,
either because of news stories, personal, disease-related concerns or simple interest in cutting edge science. Engaging those
readers, who can spread the CIRM story, and winning their approval is
critical for the agency as it faces the need to raise more millions
as it money runs out in the next few years.
CIRM has mounted much information online over
its short life. So much that good tools are needed to navigate the
site. Decisions about what should go on the home page are critical.
With the makeover, the agency now has a long-needed, home-page link to its
meetings , especially those of its governing board, which are the
single most important events at the agency.
The redesign is crisp and clean. The
new, white background makes it easier to read and is comfortable for
readers long conditioned to the black-on-white print of the books,
newspapers and magazines. The video image on the home page is larger,
which helps attract viewers. The site has long had a carload of
videos, some of which contain powerful and emotional stories from
patients.
Adams used CIRM staffers to test the
new features. She reported,

“I've had people inside CIRM (who
have been beta testing this site) tell me that they are finding
content they'd never seen before because the site is so much easier
to navigate.”

Adams and the CIRM communications team
also have pulled together important information on each grant on a
single page, including progress reports. You can find a sample here on a $1 million grant to Stanford's Helen Blau.
Adams said,

 “Now people can not only
read about what our grantees are hoping to accomplish, they can read
about what has actually been accomplished with our funding.”

Adams said another new feature is
downloadable spread sheets of information that can be manipulated by
readers offline. She said,

“Most places on the site where you
see tables, you can now download those tables to Excel. You'll notice
the small Excel icon at the lower left of the table. This feature has
long been available for the searchable grants table. Now you'll see
it on all the tables of review reports (see here for
example http://www.cirm.ca.gov/application-reviews/10877)
on the disease fact sheets (see
here http://www.cirm.ca.gov/about-stem-cells/alzheimers-disease-fact-sheet)
and other places throughout the site. This is part of an effort to
make our funding records more publicly available.”

CIRM's search engine for its web site
still needs work. A search using the term “CIRM budget 2012-2013”
did not produce a budget document on the first two pages of the
search results. A search on the term “Proposition 71,” the ballot
initiative that created CIRM, did not provide a direct link to its
text on the first two pages of search results.
Also missing from the web site, as far
as I can tell, is a list of the persons who appointed the past and
present board members as well as the dates of the board members'
terms of office. The biographies on some of the 29 governing board
members come up short. In the case of Susan Bryant, her bio does not
mention that she is interim executive vice chancellor and provost at
UC Irvine. Links also could be added to board members statements of economic interest. A list of CIRM staff members (only slightly more than 50
persons) and their titles could be added.
As for CIRM's count of visitors, CIRM
uses Google Analytics tools. Adams said,

“A unique visitor is Google's
definition (it's one of the metrics they provide). It's a visit from
a unique IP (internet protocol) address. So, if you visit our site
multiple times from one IP address during a day, you count as a
single unique visitor. (Editor's note: It is possible to have
more than one visitor from the same IP address.)

“We get ~23,000-25,000 visits per
month, or ~16,000-18,000 unique visitors. Page views are on the order
of 65,000 a month.”

Our take: The redesign of the web site
is a worthy effort and enhances CIRM's relationships with all those
who come looking for information. The agency is to be commended and
should continue its work to improve the site and its connections with
the public.

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/1OuvEMC2aTs/cyberspace-makeover-at-california-stem.html

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California Stem Cell Directors to Finalize IOM Response Next Week

By Dr. Matthew Watson

Directors of the California stem cell
agency will meet March 19 in Burlingame to complete action on
their response to blue-ribbon recommendations for sweeping changes at
the eight-year-old research enterprise.

CIRM Chairman J.T. Thomas last week
told the San Diego U-T editorial board that he regarded approval as
“largely ministerial.”
Thomas has been visiting newspaper
editorial boards around the state, touting his plan, which was
initially approved by the board in January. The main focus has been
on its provisions dealing with conflicts of interest, which would
have 13 of the 29 governing board members voluntarily remove themselves from
voting on any grant applications. The 13 are linked to recipient
institutions. Two other board members linked to recipient
institutions also sit on the board.
About 90 percent of the $1.8 billion
that has been awarded by the CIRM board has gone to institutions
linked to past and present members of the board.
In December, the Institute of Medicine cited major
problems with conflicts at the stem cell agency. It recommended
creation of a new, independent majority on the board, which would
mean that some members would lose their seats. The IOM report also
recommended a host of additional changes that have become eclipsed by
the controversy about conflicts, which were built into the board by
Proposition 71, the ballot measure that created it in 2004.
An analysis in January by the
California Stem Cell Report of the IOM report, which CIRM
commissioned at a cost of $700,000, showed that agency's response fell far short of what the IOM proposed to improve the agency's
performance.
Also on the agenda for the March 19 is
approval of applications in a $30 million effort by the agency
involving reprogrammed adult stem cells. The agency said the goal of
the initiative is “to generate and ensure the availability of high
quality disease-specific hiPSC resources for disease modeling, target
discovery and drug discovery and development for prevalent,
genetically complex diseases.”  

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/FH7dzoNWS8c/california-stem-cell-directors-to.html

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San Diego Newspaper Hails Stem Cell Agency and IOM Response

By Dr. Matthew Watson

The $3 billion California stem cell
agency hit it big in San Diego today, finally scoring an editorial
that said “arguably” the agency's largess has made the state “the
world leader in medical research.”

The San Diego U-T, the largest
circulation newspaper in the area, said the big headline about the
eight-year-old agency is “the potential for transformative medical
breakthroughs.”
The editorial noted that the agency has
long been criticized in connection with conflicts of interest. About
90 percent of the $1.8 billion the agency has awarded has gone to
institutions linked to current and past members of its board of
directors.
But the agency “is finally taking the
criticism seriously,” the newspaper said. It cited proposals that
would, if approved later this month, have 13 members of the agency's
governing board voluntarily abstain from voting on any grants that come before
the board. Twenty-nine persons sit on the board. The thirteen are
connected to recipient institutions. Two other board members are
linked to recipient institutions.
The stem cell business is no small
matter in San Diego, which is one of California's hotbeds of biotech
and stem cell research. The stem cell agency has awarded about $338
million to San Diego area institutions and businesses. Four
executives from San Diego area institutions sit on the CIRM board.
The newspaper's editorial said,

“There
remains a residue of cynicism about CIRM. Critics say the agency
board did the minimum necessary to avoid an intervention by the
Legislature – and also acted to buff the agency’s image should it
seek more bond funding from California voters before its present
funding runs out in 2017, as is now projected.

“These views
may have some merit. But on balance, we think the California
Institute for Regenerative Medicine
has – at long last –
responded properly to the fair criticism it faced. Instead of being
exasperated by CIRM, more people should be excited about the great
work it is doing.”

The editorial followed a meeting
involving the editorial board of the newspaper, CIRM Chairman
Jonathan Thomas and Larry Godlstein, director of the UC San Diego stem
cell program. The meeting was part of a CIRM campaign to generate
newspaper support for the agency's response to sweeping recommendations from a blue-ribbon study by the Institute of Medicine. The San Diego editorial is the most effusive so far.
The newspaper's biotech reporter,
Bradley Fikes, sat in on the meeting and Saturday posted video excerpts from the discussion, including a brief written summary of the content of each clip.

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/WHLDfisWzQI/san-diego-newspaper-hails-stem-cell.html

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Local View: Governor’s support for SCID screening critical – Lincoln Journal Star

By Dr. Matthew Watson

Local View: Governor's support for SCID screening critical
Lincoln Journal Star
Research in 2011 by Chan et al. in Molecular Genetics and Metabolism found SCID screening was cost effective and would save 880 life years for each year of screening in the United States. But Samantha didn't have access to SCID screening and, ...

Source:
http://news.google.com/news/url?sa=t&fd=R&usg=AFQjCNFdjpgsqPqMgQ9rY6AdB8igwhAIDg&url=http://journalstar.com/news/opinion/editorial/columnists/local-view-governor-s-support-for-scid-screening-critical/article_b44f619f-b41b-5ab8-b662-ed4b967f873c.html

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Cell Therapy for Allogeneic Stem Cell Transplant by Dr Richard Champlin – Video

By JoanneRUSSELL25


Cell Therapy for Allogeneic Stem Cell Transplant by Dr Richard Champlin
Dr Richard Champlin, Professor and Chair of the department of Stem Cell Transplant and Cellular Therapy gave an update on the role of Cell Therapy in improvi...

By: TheMedalGroup

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Cell Therapy for Allogeneic Stem Cell Transplant by Dr Richard Champlin - Video

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STEM CELL Therapy thru Laminine_Part-1(new link) – Video

By daniellenierenberg


STEM CELL Therapy thru Laminine_Part-1(new link)
STEM CELL Therapy thru laminine_part1new link. Uploaded by cabmon0001 on Mar 14 2013. cabmon 0001.

By: cabmon0001

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Shining Red Mice Help Czechs Fight Bowel Cancer, Skin Disease – Sudan Vision

By Dr. Matthew Watson


Sudan Vision
Shining Red Mice Help Czechs Fight Bowel Cancer, Skin Disease
Sudan Vision
A research group at the Institute of Molecular Genetics at the Czech Academy of Sciences is using proteins obtained from sea organisms like coral to light up mice and observe cell development under their skin without having to kill them. "We can take ...

Source:
http://news.google.com/news/url?sa=t&fd=R&usg=AFQjCNHjXdUxydpFLwOTWLDhAhvg9KHKrw&url=http://news.sudanvisiondaily.com/details.html?rsnpid%3D220497

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2013 Stem Cell Therapy #1 – Video

By daniellenierenberg


2013 Stem Cell Therapy #1
Introduction to 11 weeks of stem cell therapy in Delhi with Dr Geeta Shroff.

By: Louis Rowe

Follow this link:
2013 Stem Cell Therapy #1 - Video

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STEM CELL Therapy thru Laminine_Part-2(new link) – Video

By JoanneRUSSELL25


STEM CELL Therapy thru Laminine_Part-2(new link)
STEM CELL Therapy thru laminine_part2new link. Uploaded by cabmon0001 on Mar 14 2013. cabmon 0001.

By: cabmon0001

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Dr Alok Sharma’s Stem Cell Therapy Treatment for Cerebral Palsy – Video

By LizaAVILA


Dr Alok Sharma #39;s Stem Cell Therapy Treatment for Cerebral Palsy
dr alok sharma stem cell therapy treatment for cerebral palsy He is a case of CP with history of fullterm C section delivery and normal milestones till eight months of age when he had an episode of febrile convulsions Post convulsions he had delayed milestones After Stem Cell Therapy 1 Irrelevant speech which was excessively present before has reduced post therapy 2 His level of understanding has increased and response to following commands has improved considerably upto 25% For eg after ...

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Dr Alok Sharma Stem Cell Therapy Treatment for Muscular Dystrophy – Video

By LizaAVILA


Dr Alok Sharma Stem Cell Therapy Treatment for Muscular Dystrophy
Dr Alok Sharma Stem Cell Therapy Treatment for Muscular Dystrophy She is a known case of MD with history of gradual onset of progressive lower extremities muscle weakness noticed since 27 years of age with complaints of imbalance while walking foot drop and difficulty in stair case climbing So she was investigated and muscle biopsy confirmed diagnosis of MD After Stem Cell Therapy 1 Stamina has increased Exercise tolerance has improved 2 She can lift her leg more up while in standing 3 Hip ...

By: neurogenbsi

Follow this link:
Dr Alok Sharma Stem Cell Therapy Treatment for Muscular Dystrophy - Video

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Dr Alok Sharma Stem Cell Therapy Treatment for Muscular Dystrophy Before and After – Video

By NEVAGiles23


Dr Alok Sharma Stem Cell Therapy Treatment for Muscular Dystrophy Before and After
Dr Alok Sharma Stem Cell Therapy Treatment for Muscular Dystrophy Before and After After Stem Cell Therapy 1 Stamina has increased Exercise tolerance has improved 2 She can lift her leg more up while in standing 3 Hip flexion is easier and range has improved 4 Bending hip and knee in supine is easier 5 She can bring her leg forward in knee standing without support 6 Can now bring the knees to her chest 7 SLR range has improved Stem Cell Therapy done at Dr Alok Sharma neurogen Brain and ...

By: neurogenbsi

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Dr Alok Sharma Stem Cell Therapy for Duchenne Muscular Dystrophy in Gujarati – Video

By NEVAGiles23


Dr Alok Sharma Stem Cell Therapy for Duchenne Muscular Dystrophy in Gujarati
Dr Alok Sharma Stem Cell Therapy for Duchenne Muscular Dystrophy in Gujarati 16 years old male with history of frequent falls and being slow as compared to p...

By: neurogenbsi

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Dr Alok Sharma Stem Cell Therapy for Duchenne Muscular Dystrophy in Gujarati - Video

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Dr Alok Sharma Stem Cell Therapy Treatment for Cerebral Palsy – Video

By Dr. Matthew Watson


Dr Alok Sharma Stem Cell Therapy Treatment for Cerebral Palsy
Dr Alok Sharma Stem Cell Therapy Treatment for Cerebral Palsy He is a known case of Diplegic CP with history of full term normal delivery (vaccum) delivery a...

By: neurogenbsi

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Dr Alok Sharma Stem Cell Therapy Treatment for Cerebral Palsy - Video

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Prolotherapy | PRP | Stem Cell Therapy | The Prolotherapy Institute – prolotherapyinstitute.com – Video

By LizaAVILA


Prolotherapy | PRP | Stem Cell Therapy | The Prolotherapy Institute - prolotherapyinstitute.com
Prolotherapy | PRP | Stem Cell Therapy | The Prolotherapy Institute prolotherapyinstitutecom. Uploaded by Guillermo Mata on Mar 11 2013. Suffering from chronic pain Dr Darrow can help Prolotherapy | PRP | Stem Cell Therapy in Southern California Call The Prolotherapy Institute today Call Us Today to Make an Appointment800 7342210.

By: Guillermo Mata

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ReNeuron Group wins grants for stem cell therapy development

By raymumme

LONDON (SHARECAST) - ReNeuron Group has won two grants worth 1.2m pounds to develop its stem cell therapy.

The grants were awarded by the UK Biomedical Catalyst, a programme of public funding jointly managed by the Technology Strategy Board and the Medical Research Council.

The first award of 0.4m will be used for ReNeurons ReN009 stem cell therapy candidate for critical limb ischaemia, a severe blockage in the arteries which markedly reduces blood-flow to the extremities including hands, feet and legs.

The second award of 0.8m relates to the company's ReN003 stem cell candidate for the treatment of retinitis pigmentosa, an eye disease in which there is damage to the retina.

Michael Hunt, the Chief Executive Officer of ReNeuron, said: "We are delighted to have been successful in winning the two grants we applied for in the current round of the Biomedical Catalyst funding competition.

"This highly competitive scheme involves a rigorous peer review of applicants' technologies and commercial development plans.

"In common with other awardees, we therefore regard the grants as representing a strong independent endorsement of ReNeuron's world-class stem cell development capabilities which we hope will eventually lead to the wide-scale treatment of disease conditions where there is currently a very large unmet medical need."

Shares rose 0.86% to 2.94p at 08:52 Monday.

RD

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ReNeuron Group wins grants for stem cell therapy development

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Stem Cell Therapy Now In Davao

By LizaAVILA

With its growing popularity in the country, the so-called stem cell therapy, which was recently approved by the Department of Health (DOH), is now available in Davao City.

Dr. Luz Acosta, a Davao-born physician specializing in Ophthalmology, Oculoplastic Reconstructive Surgery, Cosmetic Surgery and recently Stem Cell Treatment, conducts the procedure after acquiring equipment from Australia and the USA. She is supported by a team that includes cardiologists, internists, and anesthesiologists who administer the laboratory tests and cardiopulmonary clearance to determine if an individual can safely undergo stem cell therapy. Having trained in this discipline abroad, she recently decided to offer this treatment after it was approved by the DoH.

As a founding member of the Philippine Society for Stem Cell Medicine that was only established last January 18, 2013 with DOH Sec. Dr. Enrique Ona as its honorary chair, Acosta is joined by doctors Jose Sabili, Melchor Santos, Christian Mancao, Leo Olarte, Bu Castro, Oscar Tinio, and Almond Derla as well as Mr. Rico Colayco as organizers of the society.

"This means that the Philippine Society for Stem Cell Medicine is the regulating body for the practice of stem cell treatment in the country," Acosta says. "Stem cell therapy is legal and safe for every medically cleared patient who wants to undergo such treatment to be rejuvenated and treated of his/her illnesses and diseases."

Acosta said that based on what was stipulated in the approved directions for stem cell therapy, the stem cell could just come from the person himself and not from the other sources like black sheep or aborted fetus, adding that sources of stem cells are fats, blood, bone marrow and umbilical cord.

"It could take five to six hours for one to undergo stem cell therapy. Harvesting is done in the first two hours, then another one to two hours for stem cell processing and activation, and the last one to two hours for treatment of stem cells back to the same patient," she said.

Popular personalities who have already publicly admitted that they had undergone stem cell therapy are former President Joseph Estrada, Senate President Juan Ponce Enrile and former Senator Ernesto Maceda, who said that they spent millions to pay for the treatment.

But Acosta said that it could be a lot cheaper here than abroad, as the cost of treatment will be in accordance to the guidelines of the Phil. Society for Stem Cell Medicine.

She said there have been very good clinical outcomes from stem cell treatments on autism, auto-immune diseases, cerebral palsy, diabetes, heart disease, liver cirrhosis, macular degeneration, multiple sclerosis, nerve damage, osteoarthritis, spinal cord injury and stroke.

"But we have to clarify here that we are not claiming stem cell therapy as a cure for cancer, though it can alleviate pain and improve patients' wellbeing while undergoing cancer therapy," she said.

See more here:
Stem Cell Therapy Now In Davao

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A Good Man Under a Bad Emperor: James Shapiro’s "Natural Genetic … – Discovery Institute

By Dr. Matthew Watson


Discovery Institute
A Good Man Under a Bad Emperor: James Shapiro's "Natural Genetic ...
Discovery Institute
It should except that, as he demonstrates in his current Huffington Post column, everything else Shapiro says on his theme of "Natural Genetic Engineering" (NGE) seems to cry out for an explanation involving some kind of deliberate art or calculation ...

Source:
http://news.google.com/news/url?sa=t&fd=R&usg=AFQjCNEi7cCwUnHY2NSxE1UK_IVuF7oBkw&url=http://www.evolutionnews.org/2013/03/a_good_man_unde069831.html

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DNA testing is Good or Bad: Let’s Discuss

By Dr. Matthew Watson

DNA, deoxyribonucleic acid it is the backbone of all living creatures on earth. It is a molecule, which is having a double helical structure and encoded with genetic instructions. It leads to the functioning of all living beings including viruses. DNA profiling is done by the forensic scientists. It depicts the nature of the DNA and act as a person identifier. By knowing the genomic sequences a scientist could easily predict the DNA of the person.

Identification Of Diseases

In this era this technology has become a boon or us in many ways. This concept of DNA testing is booming in the market like anything. It has become the latest rage specially in the health care market. Many companies are there who will promote you the test kits and let you know about the diseases like cardiac problem, any alzimers syndromes, any indication of breast cancer if have any. But here comes the argument many feeble minded people are there who will completely go against it. As the procedures includes blood testing and many people are phobic of syringes, then comes the acceptance of the disease if have any.

Benefits of DNA testing

Many women in our country are facing problem with breast cancer. As they are afraid of testing their blood and DNA. They don’t have the exact DNA marker. This is a big concern for the physicians as well. It is always recommended having a DNA testing for a healthy life. The risk factors get decreased than before and longevity will increase. Myopic thinking should be removed from the society and should learn to accept the truth. DNA testing will also give information about the allergic reaction with various pathogens. The life will be in a proper and better shape.

Detection of criminals

Normal people have a vague idea about this DNA testing which is not at all harmful. Through DNA testing crimes can also be detected. Like in the forensic lab the victim’s body will undergo a scrupulous check up and easily it will be detected about the death of the person. Many criminal lawyers take support from this process which make their job easy to detect the criminal. Though it’s not a good indication for the crime masters. By taking the blood sample or from the foot steps even, of the suspected person it will unveil the truth of the real murder. It can save our nation from crimes.

Detection of pregnancy

Many unrevealed and awful activities like rape case, illegal affairs lead to pregnancy. In many cases the male denied for becoming a father. The lady could easily raise her voice for justice, here

Comes the major role of DNA testing which will easily catch hold of the real father. Sometimes it is not safe for the pregnant woman to have DNA testing as it might cause harm to the fetus. The illegal activities in our society have inflated than before so DNA testing should play a vital role in the society of crimes.The lady will get justice and to deliver her baby.

As a whole it’s a win-win situation because some hospitals testing the DNA of the fetus take place, as an outcome they reveal the gender, which might lead to a death of a baby girl.This is an illegal activity. Some lawyers are also against this. But in this contemporary era one must believe in DNA testing to save our nation.

 

Source:
http://www.biotechblog.org/entry/dna-testing-good-bad-discuss/

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