Cure for Common Hangover? 'Pill' Mimics Action of Human Liver in Fighting ... Science Daily (press release) Additional authors of the research include Wei Wei of UCLA Engineering; Ming Yan of UCLA Engineering and the UCLA Department of Microbiology, Immunology and Molecular Genetics; Mo Yin Lau, Jay Hu, Hui Han and Cheng Ji of the Keck School of ... and more »

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http://news.google.com/news/url?sa=t&fd=R&usg=AFQjCNFXlgKHS6ZEVsiEOZF6IuiM_tulpg&url=http://www.sciencedaily.com/releases/2013/02/130220114337.htm

Michael Friedman City of Hope photo

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http://feedproxy.google.com/~r/blogspot/uqpFc/~3/DWx8xx07ZOY/city-of-hope-exec-will-leave-california.html

The $3 billion California stem cell
agency appears unlikely to make any changes in who gets the cash from
any commercial products that its research grants help finance despite
recommendations from the Institute of Medicine(IOM).

“Because CIRM is a new institution
without a track record to reassure stakeholders, and because its
finite funding timeline means as yet unknown agencies will be
enforcing these policies years down the road, CIRM should “propose
regulations that specify who will have the power and authority to
assert and enforce in the future rights retained by the state” in
CIRM IP, specifically referring to march-in rights, access plans and
revenue sharing....

“Second, as other sources of funding
become more prevalent, the agency should “reconsider whether its
goal of developing cures would be better served by harmonizing CIRM’s
IP policies wherever possible with the more familiar policies of the
BayhDole Act.”

“CIRM staff has engaged in
preliminary discussions several years ago with other agencies
regarding future enforcement of CIRM’s regulations and agreements.
Staff proposes to restart those discussions and return to the
Subcommittee (or the Board) with a formal proposal to address future
enforcement of CIRM’s IP regulations.”

“In light of the IOM’s own
recognition that it may be premature to assess whether CIRM’s
regulations will act as a deterrence to future investment, the fact
that a number of CIRM’s regulations have been codified in statutes
and CIRM’s positive progress in its industry engagement efforts to
date, although quite early, CIRM staff proposes to continue to
monitor this area and not to pursue any changes at this time.”

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http://feedproxy.google.com/~r/blogspot/uqpFc/~3/xvosTob7Zo0/monitoring-cash-and-ip-at-california.html

The California stem cell agency's
editorial road show paid off a bit again this week with a mildly
approving editorial in the Oakland Tribune.

“California
must get its stem cell house in order”

“...{T)he agency must prove that it
understands how to properly handle the public's money. …. If
the stem cell agency can establish a record as a good steward of
public dollars to finance brilliant science, it can continue to play
a useful role in stimulating and guiding research to bring the
potential cures from stem cell research to fruition.

“If it cannot do that, it will be
just another expensive Tyrannosaurus rex.”

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/tMt6gs55Yvs/half-full-half-empty-editorial-on.html

Should the scientists who evaluate
and score the applications for $3 billion in taxpayer funds be
required to publicly disclose their financial interests?

“(T)he FPPC believes that, under
state regulations, working group members (including grant reviewers)
may act as decision makers if they make substantive recommendations
that are, over an extended period, regularly approved without
significant amendment or modification by the committee. Thus, as
decision makers, working group members would need to be subject to
the conflict-of-interest code. This would mean that working groups
would be subject not only to the (public) financial disclosure requirements of
the Political Reform Act but also to the prohibition against a member
participating in a government decision in which that member has a
disqualifying financial interest and may be subject to the penalties
that may be imposed on individuals who violate that act.”

"We have given careful
consideration to your recommendation and have decided it is not
appropriate to implement at this time. In almost three years of
operation and approval of four rounds of grants, the recommendations
of the CIRM working groups have never been routinely and/or regularly
adopted by the ICOC. Until the time that such a pattern is detected,
the question you suggest we raise with the attorney general is
entirely hypothetical, and is therefore not appropriate for
submission. We will, however, continue to monitor approvals for such
a pattern and will reconsider our decision if one emerges."

“No matter what the circumstances --
if an independent observer might reasonably question whether the
individual's professional actions or decisions are determined by
considerations of personal financial gain, the relationship should be
disclosed to the public during presentations, in publications,
teaching or other public venues.”

"The public trust in what we do is
just essential, and we cannot afford to take any chances with the
integrity of the research process."

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http://feedproxy.google.com/~r/blogspot/uqpFc/~3/oma-MLcANoY/time-for-public-disclosure-of-financial.html

By Cheche V. Moral

I DID it because it worked on my wifes cousin, and because of what I read about it, says Joe Concepcion of his stem-cell therapy. ALANAH TORRALBA

Last of two parts

Jose S. Concepcion Jr., at 81, still goes to the office daily, and, to his wifes chagrin, is quite restless and bullheaded, sour if he has nothing to keep himself busy.

He does crazy things! Like, if he gets hold of a book, hell bring it and photocopy everything, says Marivic Concepcion, who has been married for 56 years to the RFM Corp. chair, Namfrel (National Citizens Movement for Free Election) founder and former trade secretary. He needs a caregiver but he wont allow it. He could fall!

Her husband, however, insists he feels excellent. I feel so good when I wake up. I dont feel tired, says the activist known to many as Joecon.

Concepcion attributes this renewed strength and vigor to a procedure he had undergone not long ago, and of which he has been a vocal and unpaid advocate: stem-cell therapy.

Astonishing effects

The tycoon received his treatment from a German doctor named Christoph Ganss, who comes to the Philippines every three or four months to speak about his company and the benefits of stem-cell banking, according to the Concepcions. Ganss is the founder of Ticeba (Tissue & Cell Banking), a tissue bank for stem cells and laboratory in Heidelberg.

The couple heard of Dr. Ganss from Ms Concepcions cousin who underwent the treatment in Germany.

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Jose “Joecon” Concepcion Jr: ‘I’m now a believer in stem-cell therapy. The proof is me!’

Baylie Faella Pre-Stem Cell Therapy at Abbott Animal Hospital in Rehoboth, MA
Baylie Faella, a 7 year old Lab pre-stem cell therapy who underwent a torn ACL repair. She also suffered from atopy (allergies) and had lesions on her body.

By: Ashraf Gomaa

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Baylie Faella Pre-Stem Cell Therapy at Abbott Animal Hospital in Rehoboth, MA - Video

Parkinson #39;s Stem Cell Therapy - Group 28 pm
BIOL 1103 Group 28 pm Stem Cell Application Assignment Sources: Euro Stem Cell research: http://www.eurostemcell.org Michael J. Fox Foundation: http://www.michaeljfox.org

By: thehaysdays

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Parkinson's Stem Cell Therapy - Group 28 pm - Video

Now, thanks to participating veterinarians like Dr. Karen Derfuss, DVM, from Branchburg Animal Hospital, who will be conducting a new double stem cell therapy procedure on Tuesday, Feb. 26, and the procedure itself, developed by MediVet America, a new kind of treatment is available for dogs, Auggie and Chloe, and other beloved pets in the Branchburg area.

This new procedure marks a major milestone in regenerative veterinary medicine, said MediVet-America spokesman, Dr. Mike Hutchinson, D.V.M., a leading practitioner in stem cell therapy who has performed more than 400 adipose-derived stem cell treatments on dogs and cats. MediVets superior results made me a believer, and Im excited to share this news with my colleagues.

The procedure uses adult animal stem cell technology and the bodys own regenerative healing power. No embryonic stem cells are used. MediVets kit and equipment enable veterinarians to remove a sample of fat from the pet, separate stem cells from the fat, then activate and inject the cells into the affected area. The entire procedure is all done in-clinic and on the same day.

Within about one month, most animals can be removed from pain and anti-inflammatory drugs. Results show animals that had been unable to climb stairs or jump, now are walking, running and playing.

MediVet is a global leader in veterinary science, with over 1,000 clinics practicing this incredible technology in the US, Mexico, Canada and 28 other countries

About the two dogs:

Auggie is a nine year old loving beagle and a Fathers Day Gift for dad. He is suffering from hip dysplasia, which is an abnormal formation of the hip socket that, in its more severe form, can eventually cause crippling lameness and painful arthritis of the joints. Derfuss is the only doctor in the area who has been certified by MediVet America to perform this double procedure. The stem cell procedure is an affordable and non-invasive alternative to FHO (femoral head osteopathy) surgery, which was originally planned for Auggie.

Chloe is a beautiful 11 year old golden retriever who suffers from bilateral arthritic hips and long term inflammation issues. It was decided to use this new technology to treat Chloes ailments as an alternative to expensive and invasive hip replacement surgery.

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First ever double stem cell therapy procedure to be performed by Branchburg veterinarian

Public release date: 21-Feb-2013 [ | E-mail | Share ]

Contact: Sooike Stoops sooike.stoops@vib.be 32-924-46611 VIB (the Flanders Institute for Biotechnology)

Cell therapy is a promising alternative to tissue and organ transplantation for diseases that are caused by death or poor functioning of cells. Considering the ethical discussions surrounding human embryonic stem cells, a lot is expected of the so-called 'induced pluripotent stem cells' (iPS cells). However, before this technique can be applied effectively, a lot of research is required into the safety and efficacy of such iPS cells. VIB scientists associated to the UGent have developed a mouse model that can advance this research to the next step.

Lieven Haenebalcke (VIB/UGent): "iPS cells have enormous therapeutic potential, but require more thorough testing before they can be used for such purposes. Using our new mouse model, we can study which mechanisms determine the identity of a cell. This knowledge is essential before we can use cell therapy for regenerative medicine."

Jody Haigh (VIB/UGent): "If we want to give cell therapy a future, then we must continue this type of research and invest in the further development of such technologies. This will result in an improved insight into cellular identity and in the long term safer options of applying iPS cells or cells derived from iPS cells in clinical studies."

Cell therapy replacing cells to provide a cure

Cell therapy is the replacement of lost or poorly functioning cells in patients. For example, such cell therapies could be used to repair the heart muscle after a heart attack, joints affected by arthritis, the pancreas in diabetes or the spine in certain forms of paralysis. This requires cells that are able to multiply in the laboratory and that can be converted to healthy cells of the desired cell type. Human embryonic stem cells meet these criteria, but they are ethically controversial.

iPS cells a promising alternative to embryonic stem cells

Shinya Yamanaka recently developed a fairly simple method to reprogram differentiated cells such as skin cells back to stem cells, so-called "induced pluripotent stem cells" (iPS cells). This earned him the Nobel Prize for Medicine in 2012 (shared with John Gurdon). These iPS cells can be generated using only 4 "reprogramming factors".

As is the case with embryonic stem cells, these iPS cells can be used to produce other cell types, such as heart muscle cells or nerve cells. They can also be cultured indefinitely and there are no ethical objections as they are not obtained from human embryos left over after IVF, but from adult individuals. Furthermore, iPS cells are obtained from the patient and this reduces the risk of rejection during therapeutic applications.

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Cell therapy a little more concrete thanks to VIB research

Feb. 21, 2013 Cell therapy is a promising alternative to tissue and organ transplantation for diseases that are caused by death or poor functioning of cells. Considering the ethical discussions surrounding human embryonic stem cells, a lot is expected of the so-called 'induced pluripotent stem cells' (iPS cells). However, before this technique can be applied effectively, a lot of research is required into the safety and efficacy of such iPS cells. VIB scientists associated to the UGent have developed a mouse model that can advance this research to the next step.

Lieven Haenebalcke (VIB/UGent): "iPS cells have enormous therapeutic potential, but require more thorough testing before they can be used for such purposes. Using our new mouse model, we can study which mechanisms determine the identity of a cell. This knowledge is essential before we can use cell therapy for regenerative medicine."

Jody Haigh (VIB/UGent): "If we want to give cell therapy a future, then we must continue this type of research and invest in the further development of such technologies. This will result in an improved insight into cellular identity and -- in the long term -- safer options of applying iPS cells or cells derived from iPS cells in clinical studies."

Cell therapy -- replacing cells to provide a cure

Cell therapy is the replacement of lost or poorly functioning cells in patients. For example, such cell therapies could be used to repair the heart muscle after a heart attack, joints affected by arthritis, the pancreas in diabetes or the spine in certain forms of paralysis. This requires cells that are able to multiply in the laboratory and that can be converted to healthy cells of the desired cell type. Human embryonic stem cells meet these criteria, but they are ethically controversial.

iPS cells -- a promising alternative to embryonic stem cells

Shinya Yamanaka recently developed a fairly simple method to reprogram differentiated cells -- such as skin cells -- back to stem cells, so-called "induced pluripotent stem cells" (iPS cells). This earned him the Nobel Prize for Medicine in 2012 (shared with John Gurdon). These iPS cells can be generated using only 4 "reprogramming factors."

As is the case with embryonic stem cells, these iPS cells can be used to produce other cell types, such as heart muscle cells or nerve cells. They can also be cultured indefinitely and there are no ethical objections as they are not obtained from human embryos left over after IVF, but from adult individuals. Furthermore, iPS cells are obtained from the patient and this reduces the risk of rejection during therapeutic applications.

Essential research possible

Before iPS cells can be used effectively and safely as a therapy, it is essential that we gain clear insight into which molecular mechanisms determine the identity of a cell; why and how a cell develops into -- for example -- a heart muscle cell, a nerve cell or a blood cell. In order to do so, Lieven Haenebalcke and Jody Haigh have developed a mouse model that will enable them to conduct this research. They succeeded in creating iPS cells from a variety of mouse cells. Furthermore, the new model allows the investigators to replace the 4 reprogramming factors in these iPS cells efficiently with specific genes in order to create targeted different cell types, such as functional heart muscle cells.

The rest is here:
Cell therapy: New mouse model promises to advance research on induced pluripotent stem cells

Stem Cell Therapy - Arthritis Therapy
Stem cell therapy for dogs, cats, and horses has been around for a few years. But as companies compete, the technology keeps improving. And today, a Hillsborough County vet clinic became only the second in the Bay Area to offer same-day procedures.

By: EhrlichAnimalHospita

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Stem Cell Therapy - Arthritis Therapy - Video

Stem Cell Therapy - Ehrlich Animal Hospital #39;s Arthritis Therapy Center
Ehrlich Animal Hospital offers several degrees of specialty arthritis therapies and treatments that may not be currently available at other local animal hospitals. Our hospital is unique in that we offer cutting edge arthritis therapy technologies: therapeutic laser treatments, injectable medications and oral medications to reduce inflammation and discomfort.

By: EhrlichAnimalHospita

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Stem Cell Therapy - Ehrlich Animal Hospital's Arthritis Therapy Center - Video

Testimonials - Stem Cell Therapy - Ehrlich Animal Hospital #39;s Arthritis Therapy Center
We love your pets and we know that you do too. Let us ensure that your pets live the longest, healthiest lives possible. Thank you for your continued confidence in our love and concern for your pet #39;s health and longevity.

By: EhrlichAnimalHospita

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Testimonials - Stem Cell Therapy - Ehrlich Animal Hospital's Arthritis Therapy Center - Video

VAIL The Vail Athletic Club, part of the Vail Vitality Center wellness experience at Vail Mountain Lodge, introduces a lecture which offers an in-depth look at new developments in cellular therapy for the treatment of joint pain. Stem Cell Therapy is a groundbreaking procedure that uses a patient's own stem cells to repair or replace damaged joint tissue. Dr. Scott Brandt of ThriveMD in Edwards is one of few physicians in the country trained in this procedure. Brandt will present details about this innovative new therapy at the Vail Athletic Club on Friday at 6 p.m.

Stem cell therapy is a minimally invasive procedure that begins with harvesting a patient's stem cells from his or her own fat reserves most often from the abdominal region. The tissue is isolated in a state-of-the-art cell-processing laboratory. The cells are then injected into the damaged joint using a minimally invasive technique with the assistance of fluoroscopic guidance. Once injected, the cells can sense proteins generated from cartilage damage and, in response, those cells have the ability to make chondrocytes cells found in healthy cartilage. This new procedure relieves the pain and limitations of arthritic joint disease without resorting to an invasive joint replacement surgery.

Brandt will discuss the process of isolating autologous adipose derived stem cells, the details of the procedure, and answer questions about this treatment for cartilage, ligament and tendon injuries.

For more information or to register call 970-476-7960. The lecture is offered as a fundraiser for the Eagle County Education Foundation and a $15 donation is suggested. Advance reservations are required and space is limited.

Continued here:
Learn more about stem cell therapy at Vail Athletic Club Friday

Beckers Muscular Dystrophy After Stem Cell Therapy in Mumbai India
He is a 12 year old and a known case of BMD with history of gradual onset of progressive lower extremities muscle weakness since age of 7 years with complaints of difficulty in climbing stairs, getting up from floor. Weakness even progressed to upper extremities with difficulty in overhead activities and frequent falls. No family history. On examination, he has grade 3 #713; muscle power in proximal muscles of both upper extremities and lower extremities and 4 in distal muscles of both upper extremities and lower extremities. He has bilateral pseudohypertrophy of calf muscles and walks on toes. Neurologically, he is hypotonic and hyporeflexic. Functionally, he is independent in most of the ADL, needs assistance in lower body dressing. On FIM he score 109. After Stem Cell Treatment 1. Reports overall feeling of freshness and energetic. 2. Can manage to walk on heels. Earlier he would walk on toes. 3. Posture has improved. Earlier he would walk with lordosis. 4. Earlier he would need maximum support for stair climbing from both railing and one hand on knee, now only uses railing to climb stairs. 5. Stamina has improved and he has increased level of confidence. 6. Sit to stand and stand to sit transfers requires less efforts. 7. Can perform overhead activities with ease and maintains for a longer time. 8. Is more active than before. 9. Speech is clear and loud followed by deep inhalation and slow rate with prolongation technique. 10. Secondary behaviors also reduced like reduced ...

By: neurogenbsi

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Beckers Muscular Dystrophy After Stem Cell Therapy in Mumbai India - Video

Hypoxic Ischaemic Brain Injury Improvement After Stem Cell Therapy in Mumbai India
He is a case of Hypoxic Brain Injury since 4 years. Because of high grade fever of "chikungunya", he got cardiac arrest and went into coma for 1 year. During comatose stage, he had sacral and Greater Trochanter sores which are all recovered and he has developed myositis ossification at bilateral hip and right elbow. Hip myositis ossification was removed surgically. After comatose stage, he has recovered in speech and voluntary control. He has developed rigidity in trunk and lower extremities. In 2011,he had history of fall while walking and had right femur shaft fracture which was treated surgically with plate and screws in place. Neurologically, he is hypertonic and hyperreflexic. On examination, he has restricted range of motion of bilateral hip, knee and ankle and right elbow. Voluntary control of lower extremities is poor while voluntary control of upper extremities is fair. He has rigidity in bilateral lower extremities and spasticity of grade 2 in upper extremities muscles. Patient is dependent for all ADL. On FIM he scores 30. After Stem Cell Treatment 1. He feels ease in getting up from supine to sit. 2. He can sit straight for some time (5-10 minutes) ,earlier easily stoop in 5-10 seconds. 3. His sitting balance is improved than before, earlier had fear to tilt sideways. 4. His spasticity in lower limb has reduced. 5. His speech has become clear and with proper pauses. 6. He can do roll over on bed with ease and less assistance from caretaker than before. Stem ...

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Hypoxic Ischaemic Brain Injury Improvement After Stem Cell Therapy in Mumbai India - Video

Inclusive Body Myopathy Improvement After Stem Cell Therapy in Mumbai India
He is a case of Inclusive Body Myopathy, since last 16 years with the history of slowness in running speed and slipping of "chappals" while walking and following foot drop. Weakness is progressive in nature and now involved muscles of all 4 limbs and trunk. Since last 3 years he is bedridden. Muscle biopsy is showing Inclusive Body Myopathy and EMG-NCV reports are showing generalized primary muscle disease. His elder sister also suffering from the same problem. Neurologically, he is hypotonic and hyporeflexic. On examination: he has grade 1+ muscle power in all 4 limbs proximally and grade 0 foot muscles and grade 3 distal muscles of upper limbs. Proximal muscle weakness is more than distal. Functionally, he is dependent in all ADL and mobility. On FIM he scores 48. After Stem Cell Treatment 1. Stamina has increased. 2. He can do suspension exercises for more range of motion and with more repetition without fatigue. 3. Now he can initiate rolling. He takes less support for rolling and turning. Earlier he used to change his position 4-5 times because of discomfort, but now he needs to change his position only once at night. 4. He can initiate supine to sit. 5. He is able to perform side lying to sitting by himself upto 70%. 6. Attempted drinking water in modified manner with right hand, which he couldn #39;t do before. Stem Cell Therapy done at Dr Alok Shrama NeuroGen Brain and Spine Institute Surana Sethia Hospital Sion-Trombay Rd, Suman Ngr Opp Corporate Park, Chembur ...

By: neurogenbsi

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Inclusive Body Myopathy Improvement After Stem Cell Therapy in Mumbai India - Video

Autism Improvement After Stem Cell Therapy in Mumbai India
He is a known case of Autism with history of full term normal delivery, cried immediately after birth. He had near normal motor milestones with delayed speech. On examination, he has poor eye contact, poor concentration, poor attention span, poor language command. He is stubborn and aggressive (decreased with rehabilitation). He goes to normal school and had good memory but poor in social communication. On ISAA scale he scores 90. On WeeFIM, he scores 77. After Stem Cell Therapy Psychology assessment: 1) His attention and concentration has improved by 25%. Previously his remedial educator would take him in a group session as he would do an activity only under a competitive spirit whereas now he can even study alone. 2) Eye contact has improved. 3) His quantity and quality of vocabulary has improved about 25%. 4) Now, he is able to form sentences of 4-5 words whereas previously his speech was bisyllables. 5) Now he is able to formulate meaningful sentences and have a meaningful conversation. 6) Now he is learning new mathematical concepts and mother and teachers feel that study wise there are real good improvements. 7) Memory has improved ie now he is able to reproduce and recollect whatever has been taught to him in the school. 8) Speech therapist mentioned that he now does not require speech therapy whereas he now requires OT and remedial education. 9) Social interaction is better ie now he can initiate and engage himself and other people into an activity or conversation ...

By: neurogenbsi

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Autism Improvement After Stem Cell Therapy in Mumbai India - Video

Spinal Cord Injury Improvement After Stem Cell Therapy in Mumbai India
She is a known case of Spinal Cord Injury since age of 1 year. After trauma she lost sensations of motor power below D6 level and on bowel bladder. MRI report showed 1) tiny focal traumatic contusion in cervical and upper dorsal spinal cord. 2) Grade 1 listhesis at C6-7 level. 3) Thin pre vertebral and anterior epidural hematoma. Initially she got good physiotherapy rehabilitation. She recovered in terms of bowel and bladder sensation, 50%. She has developed scoliosis (convexity towards right side) due to weakness of paravertebral muscles. Neurologically, she is hypertonic and hyperreflexic. She has ankle clonus. On examination: she has sensory loss below T6 level. She has grade 0 muscle power in bilateral lower extremities and near normal upper extremities strength. She is following time voiding for urination and she passes stool once in every 2-3 days. She has no pressure sores. On ASIA scale she scores "A". Functionally, she needs assistance in most ADL and wheelchair bound for mobility. On WeeFIM she scores 53. After Stem Cell Therapy 1. Exercises tolerance has increased. 2. Sitting posture is better. 3. She sits more erect now. Earlier, she used to stoop to one side. 4. Parents report that she responds to pain (being pinched on the side) now. Earlier would not be able to appreciate. Stem Cell Therapy done at Dr Alok Sharma NeuroGen Brain and Spine Institute Surana Sethia Hospital Sion-Trombay Rd, Suman Ngr Opp Corporate Park, Chembur, Mumbai -- 71. Tel : 022 ...

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Spinal Cord Injury Improvement After Stem Cell Therapy in Mumbai India - Video