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A plea for population genetics – Discover Magazine (blog)

By Dr. Matthew Watson


Discover Magazine (blog)
A plea for population genetics
Discover Magazine (blog)
Look at the header of this website, or the background to my Twitter account. Mind you, I'm pathetically informed about molecular genetics, and don't have a strong interest in the topic! I did consider using the H.W.E. or the breeder's equation for the ...

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Sunny Side Up – Milwaukee Magazine

By Dr. Matthew Watson


Milwaukee Magazine
Sunny Side Up
Milwaukee Magazine
Son of a Parisian philosopher and a well-respected watercolor painter, Matthieu Ricard, who divides his time between molecular genetics and serving as an adviser to the Dalai Lama, may have the happiest brain on the planet, according to UW researcher ...

and more »

Source:
http://news.google.com/news/url?sa=t&fd=R&usg=AFQjCNHOli4njoe_FO7KA7p0R3eNLkkziA&url=http://www.milwaukeemag.com/article/1112012-SunnySideUp

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GEN’s "Cellular Therapy Wave Finally Cresting". An overview and data set.

By Dr. Matthew Watson


We first provided a listing (with very few details) of industry-sponsored late-stage (pivotal, phase 3 and 2/3) cell therapy clinical trials on this blog late last year (see the posting here).

We are now pleased to we have worked with Genetic Engineering and Biotechnology News and Enal Razvi of Select Biosciences to provide an updated (as of June 2012) and more detailed listing of industry-sponsored late-stage (pivotal, phase 3 and 2/3) cell therapy clinical trials (excluding cell-based immunotherapies which we intend to cover in a follow-up article).

A link to the listing can be found in an article published today entitled "Cellular Therapy Wave Finally Cresting" found in the November 1, 2012 issue of GEN.  

While not my favorite title, the article is a brief - but we hope useful - overview of the sector and its pipeline.  It also provides a snapshot of the cell therapy products already in commercial distribution. 
Some will quibble about the numbers. Certainly others have published larger revenue numbers, for instance, but in our view these have almost always included revenue from cord blood banking which we have excluded.
We encourage you to read the article but for convenience here is a direct link to the spreadsheet.  Of course it's already out-dated but we'll do an update again soon here on this blog.


Hope this is useful.
--Lee


Source:
http://feedproxy.google.com/~r/CellTherapyBlog/~3/ctijFXeY01M/gens-cellular-therapy-wave-finally.html

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Study of California Stem Agency Likely to be Released in About a Month

By Dr. Matthew Watson


The $700,000, Institute of Medicine performance study of the $3 billion California stem cell agency is expected to be
released in late November or early December, the IOM said today.

In response to a question last week
from the California Stem Cell Report, Christine Stencel, senior media
relations officer for the IOM in Washington, D.C., briefly discussed
the release plans and the impact of the East Coast super-storm.
Here is the text of her response:

“The DC area escaped the worst of
Sandy’s thumping but nonetheless our schedules and planning have
been somewhat thrown off as we’re playing catch up after two days
of being shut down and some of our committee members and reviewers
are in the areas that got the brunt of the storm. We’re not sure
whether the storm will cause any delays in peer review, but we’re
working toward the goal of publicly releasing the report in late
November or early December. The study staff is working with committee
members to determine the best release format but I anticipate there
will be a press briefing. I’ll send a media advisory when we’ve
got all the details worked out.”

The stem cell agency is paying for the
report, which is examining the performance of the agency. The IOM
began its work in the summer of 2011.

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/iNEFrnWvUO0/study-of-california-stem-agency-likely.html

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Geron Weighs Biotime Bid for hESC Biz

By Dr. Matthew Watson


Geron, Inc., of Menlo Park, Ca., said
today it is assessing an offer by two of its former executives to buy
the human embryonic stem cell program that it abandoned nearly a year
ago.
Geron startled the stem cell world,
including the $3 billion California stem cell agency, when it
jettisoned the first clinical trial of an hESC therapy for financial
reasons. The agency had loaned the company $25 million just a few
months earlier. Geron repaid the loan with interest.
Geron has been mum until today about the Oct. 18 offer by Biotime, Inc., of Alameda, Ca., which is headed
by Michael West, who founded Geron in 1990. Tom Okarma, president of
Geron from 1999 to 2011, is involved with West on the deal and is now
working at Biotime.
Geron's remarks came during a
conference call on its third quarter earnings. A spokesman said the
company is working with Biotime to “assess the feasibility” of
the proposal. He said the proposed transaction is complex and the
company is seeking “additional important details.”
The spokesman declined to offer any
additional comments on the Biotime proposal when questioned following
his initial statement.  
See here and here for earlier stories on the California Stem Cell Report on the Biotime offer. 

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/4JnJvoKwHpA/geron-weighs-biotime-bid-for-hesc-biz.html

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Biotime-Geron Deal Attracts Interest from Brit Investor

By Dr. Matthew Watson


A British investment trust that has
invested in Geron says it is going to take an advantage of an offer
by an Alameda firm that is seeking to acquire Geron's human embryonic
stem cell assets.

Jonathan C. Woolf, managing director
of British & American Investment Trust PLC, said last week in a letter to its
shareholders that it is disappointed in Geron's performance and the abandonment of its hESC program last November. The sudden halt to the
program and its historic clinical trial also surprised the California
stem cell agency, which had loaned Geron $25 million just a few
months earlier. The agency has expressed an interest in continuing the trial.
Woolf said,

“We have been highly critical of
Geron management's decisions and strategy over the past 20 months, in
particular the decision in November 2011 to abruptly exit Geron's
regenerative medicine (stem cell) business in which it was the
acknowledged world leader. Since that time, Geron management has
attempted to sell or partner this business but to date has been
unable to announce any progress on this.”

Woolf's trust is not listed as a major
Geron shareholder by Morningstar, but Woolf said 17 percent of his firm's
investments are in the Menlo Park, Ca., company. The
specific size of the trust's holdings in Geron was not immediately
known.
Woolf pointed to the offer by Biotime,
Inc
., of Alameda, Ca., as a way for Geron shareholders to benefit. On
Oct. 18, Biotime proposed a complicated deal in which it would
acquire Geron's hESC program. Biotime's president, Michael West,
founded Geron in 1990. The head of the Biotime subsidiary that would acquire
the Geron assets is Tom Okarma, who was CEO of Geron from 1999 to 2011. (Here are links to brief stories on the offer: Fiercebiotech, New Scientist.)
In his letter, Woolf noted Geron's
declining stock performance. He said he is “seriously concerned”
that Geron has failed to find a buyer for the assets. Woolf said,

“These now dormant and untended
assets are inevitably losing value as competitors make progress in
Geron's absence from the field and patent protection periods
decline.”

Woolf continued,

“We believe BioTime's proposals would
make Geron's stem cell assets in combination with those of BioTime
once again the world's leading stem cell business with sufficient
resources to recommence the discontinued programmes and develop the
business further into the medium term.”

Woolf urged Geron directors and other
Geron shareholders to work with Biotime to complete the deal. Geron
has not commented on the offer.

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/va_Yea0dbF8/biotime-geron-deal-attracts-interest.html

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Confessions Of An Organic-Munching Genetic Engineer (No On Prop 37 As … – Science 2.0

By Dr. Matthew Watson


Kansas City Star
Confessions Of An Organic-Munching Genetic Engineer (No On Prop 37 As ...
Science 2.0
The AAAS says mandatory labeling is reserved for potential dangers, but genetic engineering is as safe as conventional breeding. Therefore, labels would falsely imply something wrong with GMO products. The UCS, on the other hand, supports GMO labeling ...
Safety of genetically modified foods is debated in CaliforniaKansas City Star
GMO Labeling: Does Proposition 37 Falsely Alarm or Empower Consumers?About - News & Issues
Citizen campaign to label GMO foods puts industry on defense, decades after ...Monterey County Weekly
North County Times (blog) -San Mateo Daily Journal -Food Consumer
all 196 news articles »

Source:
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[RMS] Bone Marrow Stem Cell – OSSRON – Video

By Sykes24Tracey


[RMS] Bone Marrow Stem Cell - OSSRON
Ossron is cultured autologous bone cells for bone formation. Ossron is performed by three stages : harvesting bone marrow from a patient #39;s own, cell culturing in stem cell processing center, and implanting the cultured bone cells into defect sites. Bone Marrow Stem Cell [BMSC] Bone marrow cells have shown an osteogenic potential. Only a small aspiration biopsy of bone marrow from the iliac crest is required to obtain these cells. Bone marrow stem cells are the most potent bone regenerator with abundant cell numbers, high viabilites, and highly expressed osteogenic activites. Bone marrow stem cells are able to generate tissue other than bone. These cells can be isolated, expanded in culture, and stimulated to differentiate into osteoblasts, adipocytes, chondrocytes, myocytes, neuronal cells and a variety of other connective tissue.From:SewonCellontechViews:4 0ratingsTime:06:24More inHowto Style

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cryocell | Umbilical Cord Stem Cells – Hope For a Better Tomorrow With Cord Blood Banking – Video

By Dr. Matthew Watson


cryocell | Umbilical Cord Stem Cells - Hope For a Better Tomorrow With Cord Blood Banking
http://www.cordbloodrecommendation.com However, the fees from bank to bank are pretty similar across the board. It is ready-to-use, as it is stored frozen after collecting and testing it. However, this blood can be used for non-family members and is being used to treat diseases and save lives. Secondly they regenerate cells to treat heart and circulatory diseases. Swarms of people are visiting the hospital to know more about preservation and how it is going to be beneficial for them in times of medical emergencies. The latter comes under much scrutiny and debate. However, looking at the benefit your child or may be his siblings may get 20 years down the line, you can definitely think of it as an insurance premium. 4. She was in the advanced stages of Parkinson and was looking for treatment options. How Can I Save My Baby #39;s Cord Blood?You can save it by storing it in a private cord blood bank, but if you do not save it, it will be discarded after birth. The proportion of unsuccessful searches is even greater among patients not of Northern European descent. Compared to bone marrow stem cells, cord blood stem cells are easier to harvest because they are easily obtainable from placenta after delivery and so do not involve a surgical procedure. The transplants are used to treat diseases as well as immune system problems. Most, if not all, of the major cord blood banking companies allow you to create a gift registry - similar to the popular registries at baby retailers - so that ...From:luisantafeViews:0 0ratingsTime:01:31More inTravel Events

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Fractures – Video

By Sykes24Tracey


Fractures
Stem cell therapy with fracturesFrom:MiamiFootSurgeryViews:14 0ratingsTime:00:57More inHowto Style

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The potential of regenerative medicine – Video

By NEVAGiles23


The potential of regenerative medicine
Alan Russell: The potential of regenerative medicine http://www.youtube.com http://www.ted.com Alan Russell studies regenerative medicine -- a breakthrough way of thinking about disease and injury by helping the body to rebuild itself. He shows how engineered tissue that "speaks the body #39;s language" has helped a man regrow his lost fingertip, how stem cells can rebuild damaged heart muscle, and how cell therapy can regenerate the skin of burned soldiers. This new, low-impact medicine comes just in time, Russell says -- our aging population, with its steeply rising medical bills, will otherwise (and soon) cause a crisis in health care systems around the world. Some graphic medical imagery.From:BroadcastBCViews:6 0ratingsTime:19:30More inScience Technology

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The potential of regenerative medicine - Video

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blood banks | Cryo-Cell – Cord Blood Banking Information For Parents – Video

By daniellenierenberg


blood banks | Cryo-Cell - Cord Blood Banking Information For Parents
http://www.cordbloodrecommendation.com One main reason behind the importance of saving your newborn #39;s blood is that its use is mostly geared to close relatives within your direct bloodline. Why Bank Cord Blood?Cell therapy has become a more ideal method to treat certain diseases than bone morrow transplants. Human umbilical cord blood cells are rich in mescenchymal progenitor cells and contain a large number of endothelial cell precursors. I know this all sounds very technical and expensive. Relatives or other close friends who haven #39;t gone through cord blood banking may also benefit from the stem cells that can be derived from cord blood banking if and only if they will pose a close match with the cord blood banking donor #39;s stem cells. How is it stored?At the time of the baby #39;s birth, the doctor or nurse takes the cord blood and cryogenically freezes it. 4. As for other applications, though promising, they are still in the research stage. Stem cells are early cells that are capable of developing into red and white blood cells, and platelets. Numerous study reports reveal that more than 50 per cent of the potential donors are not eligible to donate cord blood. There is no clear proof to validate that stem cells of a relative are more successful than those taken from a stranger. So, day-by-day man is trying to reach the ultimate knowledge. Even if a lot of people think that extracting stem cells from human embryos is unethical, those stem cells can also be extracted from ...From:LosHotelesEnBogotaViews:0 0ratingsTime:01:31More inTravel Events

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Irvine Scientific Offers Cell Therapy Products

By Dr. Matthew Watson

SANTA ANA, Calif.--(BUSINESS WIRE)--

Irvine Scientific, a leading cell culture media/ medical device company for more than 40 years, announced their newly launched cell therapy PRIME-XV product portfolio as part of the companys commitment to accelerate basic research and clinical applications in cell therapy and regenerative medicine. Using their expertise in cell culture media development, PRIME-XV products were designed to function as part of an integrated workflow solution in culturing primary cells, where all products have been pre-validated to decrease end user qualification time. Initially, PRIME-XV products will comprise of a serum-free medium for the expansion of human mesenchymal stromal/ stem cells (MSCs), biopreservation solutions and extracellular matrix proteins. However, Irvine Scientific intends to expand this product line to offer other cell culture media and reagents, such as stem cell qualified fetal bovine serum, tumorsphere and neural progenitor cell expansion media. Examples of existing PRIME-XV products include:

PRIME-XV MatrIS F: a recombinant human matrix protein intended for the culture of human stem/ progenitor cells under serum-free conditions. PRIME-XV MatrIS F provides an alternative substrate to the PRIME-XV Human Fibronectin product, which has a wide variety of applications in primary cell spreading and attachment.

PRIME-XV MSC EXPANSION SFM: a complete, serum-free expansion medium specifically designed for the culture of primary human MSCs derived from bone marrow and adipose tissues. This medium is supplied as a convenient one 250mL bottle and is ready-to-use without the need of additional cytokine/ growth factor supplements. MSCs cultured in PRIME-XV MSC EXPANSION SFM out performed serum-containing medium as well as leading competitors in cell expansion studies without losing their multipotent characteristics or immune modulation functions.

PRIME-XV Hypothermic Biopreservation Solution: a protein-free, defined solution intended for storage and stable shipping of cells and tissue samples under hypothermic (2-8C) condition. By preserving cells above freezing temperature, it reduces cellular stress response associated from chilling and re-warming of cells and tissues, and retains high culture viabilities after recovery. Simply replace the culture medium with this animal component-free, cGMP manufactured product for short term storage. To recover from preservation, PRIME-XV Hypothermic Biopreservation Solution is removed and replaced with growth medium of choice.

As an alternative to the PRIME-XV Hypothermic Biopreservation Solution, Irvine Scientific also carries a protein-free, defined PRIME-XV Cryogenic Preservation Solution, which allows for cryopreservation of biologics at -80C to -196C.

About Irvine Scientific

Irvine Scientific, a member of JX group, is a worldwide leader in the design, manufacture and distribution of medical devices, including Cell Therapy, Industrial Cell Culture, Cytogenetic and Assisted Reproductive Technology products. We are a large scale producer of advanced quality cell culture media for the cell therapy, industrial bioprocess, medical and diagnostic markets. Our companys extensive experience in the design of culture media, compliance with ISO and FDA regulations for class II/III medical devices and industrial scale manufacturing capacity provides our customers with unique capabilities and support. Irvine Scientific delivers products worldwide to the biopharmaceutical industry, research and medical laboratory communities.

For more information:

- Visit http://www.irvinesci.com

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Irvine Scientific Offers Cell Therapy Products

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HIV and AIDS Cure With Stem Cell Treatments – Video

By raymumme


HIV and AIDS Cure With Stem Cell Treatments
youtu.be Stem Cell Therapy Proving AIDS Responds to Stem Cell Cure, as sufferers around the world find relief and vastly improved health after stem cell treatments. Rheumatoid arthritis, immune deficiency and immune system disorders, AIDS and some forms of cancer are responding well. To learn about your condition or that of a loved one, visit StemCell-Asia.info today.From:Lek WorkerViews:6 0ratingsTime:01:03More inPeople Blogs

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FAQ-3 of 19- How Do Stem Cells Work? – Video

By Dr. Matthew Watson


FAQ-3 of 19- How Do Stem Cells Work?
youtu.be Stem Cell Proving Great Help for AIDS Sufferers Who Use Stem Cell Therapy, and this short video shows how, in a fun visual way that explains the #39;homing mechanism #39; that guides stem cells to their target (ailing, sick, dysfunctional) organs, where the stem cells differentiate, and live to strengthen and heal the previously diseased organ. For more information, visit StemCell-Asia.info today.From:Harvey WallbangerViews:8 0ratingsTime:01:01More inScience Technology

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HIV and AIDS Cure With Stem Cells Now Accepted Stem Cell Therapy – Video

By Sykes24Tracey


HIV and AIDS Cure With Stem Cells Now Accepted Stem Cell Therapy
youtu.be Whether as differentiated or undifferentiated, whether from sheep stem cells or from rabbit; delivered frozen or fresh, today #39;s stem cell therapies are showing real promise and helping HIV-AIDS sufferers around the world, today! Cautious not to claim they can cure ANYTHING, today #39;s ethical clinics offer hope for AIDS-HIV sufferers worldwide, although the one Thai clinic licensed by the German stem cell technique is in Bangkok. For information to help you make an informed, personal decision, check out StemCell-Asia.info today.From:Kerry DeanViews:7 0ratingsTime:01:03More inPeople Blogs

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HIV and AIDS Cure With Stem Cells Now Accepted Stem Cell Therapy - Video

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FAQ-4 19- What Chance Stem Cells HELP Me After Stem Cell Therapy? – Video

By Dr. Matthew Watson


FAQ-4 19- What Chance Stem Cells HELP Me After Stem Cell Therapy?
youtu.be As differentiated or undifferentiated, whether from sheep stem cells or from rabbit; delivered frozen or fresh, today #39;s stem cell therapies are showing real promise and helping HIV-AIDS sufferers around the world, today! Cautious not to claim they can cure ANYTHING, today #39;s ethical clinics offer hope for AIDS-HIV sufferers worldwide, although the one Thai clinic licensed by the German stem cell technique is in Bangkok. For information to help you make an informed, personal decision, check out StemCell-Asia.info today.From:John PepperViews:0 0ratingsTime:01:38More inPeople Blogs

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FAQ-4 19- What Chances for Stem Cell Success When I Get Stem Cell Therapy? – Video

By Dr. Matthew Watson


FAQ-4 19- What Chances for Stem Cell Success When I Get Stem Cell Therapy?
youtu.be Whether as differentiated or undifferentiated, whether from sheep stem cells or from rabbit stem cells; delivered frozen or fresh, today #39;s stem cell therapies are showing real promise and helping HIV-AIDS sufferers around the world, today! Cautious not to claim they can cure ANYTHING, today #39;s ethical clinics offer hope for AIDS-HIV sufferers worldwide, although the one Thai clinic licensed by the German stem cell technique is in Bangkok. For information to help you make an informed, personal decision, check out StemCell-Asia.info today.From:VeteransRecallViews:1 0ratingsTime:01:38More inPeople Blogs

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FAQ-4 19- What Chances for Stem Cell Success When I Get Stem Cell Therapy? - Video

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[RMS] C-Class Stem Cell Processing Center (SPC) – Video

By NEVAGiles23


[RMS] C-Class Stem Cell Processing Center (SPC)
C-Type Member practice stem cell therapy with setting up C-class Stem cell Processing Center. Single platform with necessary equipments (including the ones for quality control tests) built in single space for the production of Chondron processing room, preparation room, utility room.From:SewonCellontechViews:1 0ratingsTime:00:46More inHowto Style

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Stem Cell Therapy for osteoarthritis Cosmetic Surgery Thailand Review – Urban Beauty Thailand – Video

By Sykes24Tracey


Stem Cell Therapy for osteoarthritis Cosmetic Surgery Thailand Review - Urban Beauty Thailand
Plastic Surgery Thailand Cost Reviews Adipose-derived stemcell fat graft + PRP + Fat transfer for natural augmentation on all part of body such as Face, Breast, Butt, Hand etc. Adistem is originally and can deliver Stemcell for cell survial more than 300millions cell.Compare with other methods such as CAL, Adistem is most Cell Survival among others result is permanantly. Normally, the cost is around 350000baht/appx $11667usd but we can offer as $9000usd/appx 270000THB all inclusive with 5 nights facilities. Urban Beauty Thailand is a bespoke One-Stop Travel and Beauty Solution. Arranging the best medical tourism package for you, from your flights, to whichever Cosmetic Surgery, Beauty Treatments or Dental Treatments are right for you, at the right treatment center, whether in Bangkok, Phuket, Koh Samui, or Pattaya. We also arrange excursions and holiday activities during your stay. Cosmetic surgery Thailand, Plastic surgery Thailand cost reviews. Provide FREE Consultation olivia@urbanbeautythailand.com http://www.urbanbeautythailand.comFrom:UrbanBeautyThaiViews:15 1ratingsTime:07:21More inTravel Events

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Stem Cell Therapy for osteoarthritis Cosmetic Surgery Thailand Review - Urban Beauty Thailand - Video

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