International Stem Cell Corporation to Present at the Southern California Investor Conference on Monday, August 29th
By Dr. Matthew Watson
International Stem Cell Corporation (OTCBB: ISCO) announced today that Kenneth Aldrich, Chairman, will be presenting at the 2011 Southern California Investor Conference on Monday, August 29, 2011 at 1:30 p.m. Pacific (4:30 p.m. Eastern). The conference takes place at The Island Hotel in Newport Beach, California.
The Southern California Investor Conference is the only conference focused exclusively on the wealth of exciting growth companies from Southern California. The annual one-day conference features more than 35 companies from the region presenting to attendees from throughout the nation. The conference is open to the public and investors can find a list of 2011 presenting companies and registration information at http://www.CaliforniaStocks.com
A webcast of the International Stem Cell Corporation presentation will be accessible online at http://events.powerstream.net/002/00271/20110829_SCIC_T2/ or from the link on the Company's web site at http://www.internationalstemcell.com. An archived version will be available for 30 days.
About International Stem Cell Corporation
International Stem Cell Corporation is focused on the therapeutic applications of human parthenogenetic stem cells and the development and commercialization of cell-based research and cosmetic products. ISCO's core technology, parthenogenesis, results in the creation of pluripotent human stem cells from unfertilized oocytes (eggs). hpSCs avoid ethical issues associated with the use or destruction of viable human embryos. ISCO scientists have created the first parthenogenic, homozygous stem cell line that can be a source of therapeutic cells with minimal immune rejection after transplantation into hundreds of millions of individuals of differing genders, ages and racial background. This offers the potential to create the first true stem cell bank, UniStemCell™. ISCO also produces and markets specialized cells and growth media for therapeutic research worldwide through its subsidiary Lifeline Cell Technology, and cell-based skin care products through its subsidiary Lifeline Skin Care. More information is available at http://www.internationalstemcell.com.
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International Stem Cell Corporation
Kenneth C Aldrich, Chairman
760-940-6383
kaldrich@intlstemcell.com
or
Lippert/Heilshorn & Associates
Don Markley
310-691-7100
dmarkley@lhai.com
Source:
http://intlstemcell.blogspot.com/feeds/posts/default?alt=rss
WikiLeaks: Ambassador Warlick: Bulgarian Government Walks Tight Rope on GMOS – Novinite.com
By Dr. Matthew Watson
Novinite.com | WikiLeaks: Ambassador Warlick: Bulgarian Government Walks Tight Rope on GMOS Novinite.com (SBU) Summary: A draft law that would bring Bulgaria's current restrictive biotechnology regime into EU compliance has been seized upon by anti-GMO groups. As a result, as a tactical response, the government is proposing, as a supplement to the draft ... |
Source:
http://news.google.com/news?q=biotechnology&output=rss
Spinal Cord Injury – Stem Cell Therapy
By daniellenierenberg
Franklin is a patient with spinal cord injury. This video is the experience of Franklin R. who underwent stem cell treatment to improve his condition after an accident that left him paraplegic.
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Spinal Cord Injury - Stem Cell Therapy
Cardiac Stem Cells in End-Stage Human Failing Hearts: Are they functional?
By Dr. Matthew Watson
Sunjay Kaushal USA river-valley.tv
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Cardiac Stem Cells in End-Stage Human Failing Hearts: Are they functional?
Stem cell therapy in Guatemala – (closer than China)
By NEVAGiles23
Medicenter, a Stem Cells clinic in Guatemala, Central America. Mr. Gemperline had a stem cell transplantation
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Stem cell therapy in Guatemala - (closer than China)
Regenerative Medicine With Stem Cell Therapy Injections at an Arizona pain clinic (602) 507-6550
By NEVAGiles23
Amniotic Fluid Based Stem Cell Injections are being offered at Preferred Pain Center in Arizona. The injections offer an opportunity to harness the body's regenerative potential and exponentially increase it: 1) Anti-inflammation 2) Hyaluronic Acid 3) Stem Cells 4) Non-steroidal, non-embryonic treatment Pain relief plus potential regeneration of cartilage and soft tissues such as rotator cuff and ligaments.
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Regenerative Medicine With Stem Cell Therapy Injections at an Arizona pain clinic (602) 507-6550
Stem cells acquired from human skin
By daniellenierenberg
Japanese scientists from Kyoto University, led by Professor Shinya Yamanaka and American researchers from the University of Wisconsin, led by James Thomson managed to create multifunctional stem cells from human skin. Earlier, generation of stem cells required cloning or use of human embryos.
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Stem cells acquired from human skin
Vitamin D deficiency unquestionably linked to bone fractures
By Dr. Matthew Watson
Recent research from Scotland reinforces the longstanding medical opinion that vitamin D deficiency leads to a significantly increased risk of bone fractures.
Among people with hip fractures referred to the Scottish fracture liaison service, 98 percent test positive for serious deficiencies in vitamin D. Supplementation with the vitamin, on the other hand, significantly reduces the risk of repeat fractures.
"Taking a supplement can make a difference quite quickly," said Stephen Gallacher, head of the liaison service. "Bone density can increase by 20 percent in a few months with enough vitamin D."
"We have found we can reduce fractures by something like 30 to 50 percent. It is our belief that we can significantly reduce the risk of fractures in the population by giving people anti-osteoporosis therapy and vitamin D supplements."Read more...
The Cleverness Of The Apes (GALLERY) – Global Animal
By Dr. Matthew Watson
The Guardian (blog) | The Cleverness Of The Apes (GALLERY) Global Animal (GREAT APES/ANIMAL SCIENCE) In “Rise of the Planet of the Apes,” experiments with genetic engineering lead to an incredibly intelligent species of ape. In reality, these non-human primates are in fact very smart and have better, faster memories than we ... Movie Review: Rise of the Planet of the ApesWishaw Press Rise of the Planet of the Apes – 'Human, all too human'The Guardian (blog) |
Source:
http://news.google.com/news?q=genetic-engineering&output=rss
2nd International Festival of Biotechnology – India: – Sunday Observer
By Dr. Matthew Watson
Sunday Observer | 2nd International Festival of Biotechnology - India: Sunday Observer Nalanda College, Colombo won first place at the 2nd International Festival of Biotechnology held at the CMS Rajendra Nagar Campus - 1 Lucknow, India. Fifty-six schools representing Sri Lanka, India, Bangladesh, Nepal, Bhutan, Pakistan and Russia ... |
Source:
http://news.google.com/news?q=biotechnology&output=rss
International Stem Cell’s Q2 Revenues Nearly Triple by Deborah Sterescu
By Dr. Matthew Watson
Source:
http://intlstemcell.blogspot.com/feeds/posts/default?alt=rss
International Stem Cell Corporation Announces Second Quarter 2011 Financial Results and Corporate Events
By Dr. Matthew Watson
International Stem Cell Corporation Kenneth C. Aldrich, Chairman 760-940-6383 kaldrich@intlstemcell.com Or Ray Wood, CFO 760-940-6383 rwood@intlstemcell.com |
Source:
http://intlstemcell.blogspot.com/feeds/posts/default?alt=rss
Part 3: The Ellis Martin Report with Ken Aldrich of Int Stem Cell Corp (ISCO.OB)
By Dr. Matthew Watson
Source:
http://intlstemcell.blogspot.com/feeds/posts/default?alt=rss
Cutting edge classes coming to one Tampa high school – Central Florida News 13
By Dr. Matthew Watson
Central Florida News 13 | Cutting edge classes coming to one Tampa high school Central Florida News 13 (BN9 photo/Robert Hahn) Middleton High, a magnet school in Tampa, is offering courses in biomedical science and biotechnology to help prepare students for the 21st century. By Robert Hahn, Reporter An exciting new program is coming to Middleton High ... |
Source:
http://news.google.com/news?q=biotechnology&output=rss
Embryonic stem cell therapy in China (www.esctherapy.com)
By LizaAVILA
Since 2002, ESC therapy has treated over 10000 patients with degenerative diseases, injury and cancer, now it has move on to help people to delay ageing as disease usually comes from weaken and aged cells. ESC therapy provides young healthy cells to replace aged and mutated cells in order to prevent disease and delay ageing.
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Embryonic stem cell therapy in China (www.esctherapy.com)
"Bone Marrow Stem Cells" Donald Kohn
By NEVAGiles23
"Bone Marrow Stem Cells: Developing New Therapies in the Fight Against Disease"- Donald Kohn, January 18, 2011 Dr. Donald Kohn, UCLA professor of microbiology, immunology and molecular genetics, his research group at the Kohn Lab focus on developing new therapies for genetic diseases of the blood cells using gene therapy methods to correct hematopoietic stem cells. His laboratory performs studies on gene transfer, expression and immune response and then translates the findings into clinical trials.
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"Bone Marrow Stem Cells" Donald Kohn
Govt panel hand in GM botch-up – Calcutta Telegraph
By Dr. Matthew Watson
Treehugger | Govt panel hand in GM botch-up Calcutta Telegraph 13: Government agencies have helped a crop biotechnology company involved in genetic engineering of brinjal in its alleged violation of a 2005 law that regulates access to India's biodiversity, a state biodiversity official and environmental groups ... Bt brinjal: NBA to act against Mahyco, MonsantoIndian Express NBA may act against Mahyco / Monsanto, company claims all permissions in placefnbnews.com |
Malaysia Secures RM2 Billion Industrial Biotechnology Investment In ECER – Bernama
By Dr. Matthew Watson
Business Recorder | Malaysia Secures RM2 Billion Industrial Biotechnology Investment In ECER Bernama PUTRAJAYA, Aug 12 (Bernama) -- Malaysia has secured a RM2 billion industrial biotechnology investment in the East Coast Economic Region (ECER). South Korea's CJ Cheiljedang Corporation and France's Arkema SA today announced the setting up of the ... Malaysia Receives US$660 Million Biotech Investment From S Korea & FranceAsian Scientist Magazine Korea, France to invest RM2b in ECER biotech sectorThe Edge Malaysia ECER gets RM2bil boostMalaysia Star The Malaysian Insider -Business Times - Malaysia -AFP all 19 news articles » |
Good Data? $100. Good Product Development? $100. Good Commercialization Strategy? Priceless.
By Dr. Matthew Watson
I'm not going to fool anyone into believing I'm a therapeutic product development expert but that's not going to stop me from making a few humble observations in light of the Dendreon "fiasco" of last week which I have no doubt will one day be considered an unfortunate pothole on their road to eventual success.
(though perhaps not before certain current management finds themselves polishing their CVs or retiring to spend their time alternating between their yachts and the courtroom defending their questionable stock trading antics)
NWBT HIGHLIGHTS COST EFFECTIVENESS OF DCVAX® IN VIEW OF RECENT IMMUNOTHERAPY PRICING CONCERNSNorthwest Biotherapeutics' (OTC.BB: NWBO)... DCVax® immune therapies for a broad range of cancers (including prostate, brain, ovarian and others) hold the promise, based on available data to date, of being cost effective and priced below other immune therapies while still providing substantial profit margins for the Company and longer survival for patients.The investor concerns in the news relate to the pricing and reimbursement of Provenge for late stage, metastatic prostate cancer. Provenge is priced at $93,000 for one month of treatment and was approved by the FDA based upon having added 4.5 months of patient survival (to reach overall survival of 25.9 months).NWBT’s DCVax® will be priced in the range of $37,000 per year for up to 3 years of treatments. In NWBT’s Phase I/II multi-center clinical trial in late stage, metastatic prostate cancer, DCVax® added 18 months of patient survival (to reach overall survival of 38.7 months). DCVax® has previously been cleared by the FDA for a 612-patient, randomized, controlled Phase III trial, although the trial has not yet begun. As is typical before a Phase III trial, the manufacturing processes and product costs have already been determined.......The key to the substantial pricing advantage of DCVax® is NWBT’s proprietary batch manufacturing process together with its cryopreservation technology for frozen storage of the finished vaccine. NWBT has spent a decade developing and improving its manufacturing and cryopreservation processes. The manufacturing of personalized, living cell products is expensive. But the frozen storage of living cells is quite low-cost – once the specialized freezing technology is worked out for a particular type of cells (the culture conditions, rate of freezing, density of cells and many other factors).NWBT’s manufacturing methods produce – in a single manufacturing run – a large batch of personalized DCVax® product for 3 years of treatments are much less costly than separate manufacturing runs for each treatment. The technology for freezing the master immune cells (dendritic cells) which comprise DCVax® enables thesecells to remain frozen for years and, when needed, to be thawed and “come back to life” with full potency.This approach makes DCVax® an "off the shelf” product [for that patient] for several years of treatments after just one manufacturing run. In contrast, Dendreon must do a separate manufacturing run for each one month of treatments. In addition, Dendreon's Provenge product is fresh and not cryopreserved, which limits its shelf life to at most a few weeks.Another important factor in the cost effectiveness of DCVax® is its simplicity and ease of administration. DCVax® is delivered as a small intra-dermal injection under the skin, similar to a flu shot. As such, it can be administered in any physician’s office or clinic. There is no lengthy intravenous infusion, with the attendant patient discomfort, cost and need for a specialty infusion center. In contrast, Dendreon’s Provenge is delivered by intravenous infusion.The cost effectiveness of NWBT’s DCVax® is enhanced by the fact that DCVax® is targeting a portion of the prostate cancer market that is 4 times the size of the market segment that Dendreon’s Provenge is currently targeting....
- science (e.g., MOA, characterization, etc),
- clinical effect, and
- how to optimize its commercial viability - a big part of which is what we think of as 'product development'.
International Stem Cell Corporation: A Company with Scores of Potential by Deborah Sterescu
By Dr. Matthew Watson
International Stem Cell Corp (OTCBB:ISCO) is a company to watch this year, with several promising developments in store, according to a conference call with investors this morning.
The company, whose parthenogenetic stem cell technology can be used to derive pluripotent stem cells, meaning they can be transformed into any cell type in the body, has many important advantages at its fingertips.
Regenerative medicine is a market that is set to boom in the coming years, as more and more companies are developing therapies based on stem cell use. International Stem Cell's long-term goal is to be a universal supplier of stem cells for not just one, but a host of therapies.
The company's parthenogenetic stem cells are derived from unfertilized eggs, avoiding the ethical issues behind the destruction of viable human embryos, and giving cell-therapy companies one big reason to chose International Stem Cell as their supplier of choice when the time is right.
These parthenogenetic cells, like embryonic cells, also have the capacity to become almost any cell type in the body, but have demonstrated they are better in terms of the immune system, as one single stem cell line can be genetically matched to millions of people, reducing the need for immunosuppressants.
The company holds the world's largest collection of research-grade human parthenogenetic stem cell (hpSC) lines, which it uses along with its partners to investigate cellular therapies for a number of incurable human diseases.
Its plan is to establish a US bank of its clinical-grade human parthenogenetic stem cells that will be capable of being immune-matched to millions of patients, so that a physician could call up and request a specific cell type for people. The company, which recently received approvals to enroll around 3 US donors for its bank, already has a collection of ten human parthenogenetic stem cell lines used for research purposes, which were derived outside the US.
These cell lines could potentially be used to cure a number of diseases, including cancer, heart disease, liver disease, among many others. Already, the company has several trials in the works, and has successfully demonstrated in pre-clinical animal studies that its stem cells can be used to create viable liver cells.
Currently, efficacy tests in rat models are in progress for the liver cells, with results anticipated soon. If successful, the company said it plans on aggressively initiating the FDA process, with the aim of beginning first stage clinical trials sometime in 2012. The hope is that International Stem Cell will attain Fast Track designation, as few alternative options are available to patients suffering from liver disease.
The company also has trials in the works for Parkinson's disease and diseases of the eye, and is actively looking for collaborative or joint venture opportunities, as well as in-licensing and out-licensing arrangements.
In addition to its hugely potentially valuable stem cell therapy business, the company also two other operations that are set to generate revenue in the meantime. Lifeline Cell Technology, which saw sales grow by 35% in the first quarter, develops manufactures and markets the Lifeline brand of cell-culture products, which are used by researchers to grow human cells for pre-clinical research.
The subsidiary's products are developed using parent International Stem Cell's technology, and the company expects that as trials for researchers progress into more advanced stages, its technology will be embedded in this progress, potentially generating hundreds of millions of revenue.
In the last quarter, Lifeline Cell gained over 200 new customers due to new product introductions and the development of distribution channels internationally, a strategy it plans to continue.
Lastly, International Stem Cell's Lifeline Skin Care business sells skin care products based on its stem cells, having a very successful launch at the end of last year. The company planned on selling 1,000 products, but sold 7,000 initially, and plans to aggressively kick start major marketing initiatives again in September.
International Stem Cell is a company with scores of upside potential, and though future capital raising has not been ruled out, it has a facility that allows it to draw equity as necessary.
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