In December 2010, we received authorization from Swissmedic, the Swiss regulatory agency for therapeutic products, to initiate a Phase I/II clinical trial in Switzerland of our HuCNS-SC human neural stem cells in chronic spinal cord injury. Enrollment in this trial is expected to begin inearly 2011.

Learn more about our clinical trial in spinal cord injury

Human neural stem cells promote long-term functional motor recovery. Learnmore

Human neural stem cells were transplanted into a group of spinal-cord injured mice and their motor function over time was compared against a control (non-transplanted) group of similarly injured mice as measured by the BBB score (a standard measure of function). The motor function of the transplanted mice was shown to be higher to a statistically significant degree. When the transplanted human cells were subsequently ablated by the researchers using Diphtheria toxin (DT), the greater function of the transplanted group was lost, demonstrating that the presence of the human cells was necessary for the functional motor recovery.

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DT treatment to ablate transplanted cells

Restored motor function lost

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StemCells, Inc. - Therapeutic Programs: Spinal Cord Injury